Anticoagulants may increase the risk of cerebral hemorrhage
-
Last Update: 2020-12-07
-
Source: Internet
-
Author: User
Search more information of high quality chemicals, good prices and reliable suppliers, visit
www.echemi.com
recently, a new study found that the use of anticoagulant drugs may change the rate of hematoma under the epidural. These anticoagulant drugs include low-dose aspirin, vitamin K antagonists (e.g. warfarin), clopidogre and oral anticoagulants. The paper was published
.
David Gaist of the University of Denmark and colleagues analyzed data from 1,010 patients with epidural hematoma and more than 400,000 control groups. Participants in the study group, aged 20 to 89, first developed subdural hematoma between 2000 and 2015, with 47 percent of them taking anticoagulant drugs. It was found that there was an association between the occurrence of hematoma under the epidural and the use of anticoagulant drugs.
the researchers noted that low-dose aspirin posed a lower risk in terms of the risk associated with epidural hematoma, clopidogrely and direct oral anticoagulants were moderate risk, and vitamin K antagonists (VKA) were at higher risk. The use of more than one anticoagulant drug at the same time was associated with a significant increase in the risk of subdural hematoma, which was particularly evident when VKA was combined with an antiplate drug (e.g. low-dose aspirin or clopidogre), with the exception of low-dose aspirin in combination with diazepam, an antiplate plateplot drug.
addition, the data show that between 2000 and 2015, the use of anticoagulant drugs increased in the general population, while the overall rate of hematomas under the epidural also increased, with the largest increase occurring in patients over the age of 75.
the study adds another evidence to the risk-benefit analysis of anticoagulant drug use. These drugs have long been known to bring overall net benefits in patients with clear treatment guidelines. (Source: Science Network Zhang Zhang)
This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only.
This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of
the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed
description of the concern or complaint, to
service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content
will be removed immediately.