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    Home > Active Ingredient News > Endocrine System > Antioxidants (Basel): Relationship between vitamin C status and body weight in patients with type 1 and 2 diabetes mellitus and various degrees of renal insufficiency

    Antioxidants (Basel): Relationship between vitamin C status and body weight in patients with type 1 and 2 diabetes mellitus and various degrees of renal insufficiency

    • Last Update: 2022-04-17
    • Source: Internet
    • Author: User
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    Background: Diabetes mellitus is a complex disease characterized by chronic metabolic disturbances and potentially life-threatening complications


    Diabetes is a complex disease characterized by chronic metabolic disturbances and potentially life-threatening complications


    Methods: This study retrospectively investigated vitamin C status in 136 adult outpatients with type 1 and type 2 diabetes mellitus (T1 DM/T2 DM), focusing on indicators of renal function and metabolic health, including body weight


    RESULTS: In the T1 DM group (n=73), the median plasma vitamin C concentration was 33 (18, 48) µmol/L, with a vitamin C deficiency rate of 37% and a vitamin C deficiency rate of 12%


    Table 1.


    Table 1.


    Figure 1.


    Figure 1.


    Table 2.


    Table 2.


    Figure 2 The relationship between plasma vitamin C and renal function and hypertension: (A) The plasma vitamin C concentration in patients with macroalbuminuria (ACR>30) was significantly lower than that in patients with normal renal function (ACR<3; *p=0.


    Figure 2 The relationship between plasma vitamin C and renal function and hypertension: (A) The plasma vitamin C concentration in patients with macroalbuminuria (ACR>30) was significantly lower than that in patients with normal renal function (ACR<3; *p=0.


    In conclusion, body weight was a significant predictor of low vitamin C levels in diabetic patients


    Vitamin C Status in People with Types 1 and 2 Diabetes Mellitus and Varying Degrees of Renal Dysfunction: Relationship to Body Weight.


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