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    Home > Active Ingredient News > Digestive System Information > AP&T: Hepatic encephalopathy is an independent risk factor for new infections in patients with acute decompensated cirrhosis

    AP&T: Hepatic encephalopathy is an independent risk factor for new infections in patients with acute decompensated cirrhosis

    • Last Update: 2022-04-22
    • Source: Internet
    • Author: User
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    Overt hepatic encephalopathy (OHE) causes up to one-third of cirrhotic patients to experience worsening of cirrhotic disease progression at some point in the clinical course
    .


    HE is also a major factor in repeat hospitalizations in patients with cirrhosis and is associated with a high mortality rate


    Overt hepatic encephalopathy (OHE) causes up to one-third of cirrhotic patients to experience worsening of cirrhotic disease progression at some point in the clinical course


     

    The researchers divided patients into four groups; no OHE and infection (n = 352); no infection but OHE (n = 221); no OHE but infection (n = 100) and OHE and infection (n = 100) n = 86)
    .


    In multivariate analysis, OHE (OR, 1.


    Figure: Incidence of Hepatic Encephalopathy

     

    The findings suggest a significant relationship between OHE and the risk of new infections in the context of cirrhosis
    .


    Therefore, patients with OHE should be considered to be at high risk for new infections, and antibiotics


    The findings suggest a significant relationship between OHE and the risk of new infections in the context of cirrhosis


    Eman Alabsawy.


    Overt hepatic encephalopathy is an independent risk factor for de novo infection in cirrhotic patients with acute decompensation.
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