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    Home > Active Ingredient News > Digestive System Information > AP&T: The role of smoking in the pathogenesis of functional dyspepsia and irritable bowel syndrome

    AP&T: The role of smoking in the pathogenesis of functional dyspepsia and irritable bowel syndrome

    • Last Update: 2021-08-02
    • Source: Internet
    • Author: User
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    Worldwide, functional gastrointestinal disorders (FGID) is a high incidence of benign disease, two of the best known is the irritable bowel syndrome (IBS) and functional digestive poor (FD), these diseases To a large extent, it will have a negative impact on the quality of people's lives, work and interpersonal relationships
    .


    IBS is predominantly diarrhea (IBS-D), constipation (IBS-C) or mixed mode (IBS-M), while FD may manifest as early fullness or fullness after a meal (postprandial distress syndrome, PDS) or Epigastric pain syndrome (EPS)


    Worldwide, functional gastrointestinal disorders (FGID) is a high incidence of benign disease, two of the best known is the irritable bowel syndrome (IBS) and functional digestive poor (FD), these diseases To a large extent, it will have a negative impact on the quality of people's lives, work and interpersonal relationships


     

    Researchers conducted three population-based endoscopy studies in Sweden, with a total of 2560 community individuals (average age 51.
    5 years, male 46%)
    .


    IBS patients, FD patients, and patients with related symptoms were assessed using a validated abdominal symptom questionnaire, and whether they smoked was obtained from standardized questions during clinical visits


     

    The results of the study showed that smokers had a significantly higher chance of developing postprandial distress syndrome (FD-PDS) (OR 10-19 cig/day = 1.
    42, 95% CI 1.
    04-1.
    98; P= 0.
    027, OR ≥20 cig/day = 2.
    16, 95% CI 1.
    38 -3.
    38, P= 0.
    001) but the symptoms of patients with epigastric pain are not related to smoking
    .


    People who smoke 20 or more cigarettes a day have a significantly higher chance of IBS diarrhea (OR = 2.


    Figure: The effect of smoking on the gastrointestinal tract

          This study confirmed that smoking is an important environmental risk factor for postprandial distress syndrome.
    Heavy smokers are more than twice as likely to develop PDS
    .


    The role of smoking in IBS diarrhea may also be important


          This study confirmed that smoking is an important environmental risk factor for postprandial distress syndrome.


     

    Original source:

    Nicholas J.


    Role of smoking in functional dyspepsia and irritable bowel syndrome: three random population-based studies.


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