Application and Prospect of freeze dryer

It is reported that at present, vacuum freeze-drying technology has been widely used in bioengineering, pharmaceutical industry, food industry, material science, agricultural and sideline products deep processing and other fields Pharmaceutical industry: air conditioning refrigeration market experts introduced that freeze-drying of drugs mainly includes Western medicine and traditional Chinese medicine Freeze drying of Western medicine has been developed in China Many large pharmaceutical factories have freeze drying equipment In terms of injection, freeze-drying technology is widely used, which improves the quality and storage period of drugs, and brings benefits to both doctors and patients But at present, there are not many kinds of freeze-dried drugs, the price of products is high, and the drying process is not advanced In the aspect of traditional Chinese medicine, at present, it is only limited in the freeze-drying of a small amount of traditional Chinese medicine, such as ginseng, pilose antler, yam, Cordyceps and so on A large number of Chinese patent medicines have not yet adopted the freeze-drying process, which is far behind the foreign countries Japan carried out the "Western preparation of Chinese medicine" several years ago, which changed the boiling method of traditional Chinese medicine, solved the tradition that traditional Chinese medicine can not be made into injections or tablets, and also solved the problem that traditional Chinese medicine does not cure acute diseases Therefore, the research on freeze-drying technology and products of traditional Chinese medicine in China has great potential Field of Bioengineering: in the field of biotechnology products, freeze-drying technology is mainly used in the production of serum, plasma, vaccine, enzyme, antibiotic, hormone and other drugs; biochemical inspection drugs, immunology and bacteriology inspection drugs; long-term preservation of blood, bacteria, artery, bone, skin, cornea, nerve tissue and various organs The current situation and development of freeze-drying equipment are inseparable from the application and equipment Up to now, the forms of freeze-drying equipment are mainly divided into two categories: intermittent type and continuous type The scale of equipment is from less than one square meter to dozens of square meters 1 Intermittent freeze-drying equipment intermittent freeze-drying equipment is suitable for small batch production of many varieties, especially for seasonal food production in the food field Single machine operation is adopted If one equipment fails, normal operation of other equipment will not be affected The intermittent freeze-drying equipment is convenient to control the heating temperature and vacuum degree in different stages of material drying It is easy to process, manufacture and maintain the equipment However, the operation of loading, unloading and starting takes up a lot of time, so the equipment utilization rate is low and the production efficiency is not high 2 In recent years, continuous freeze-drying equipment has been explored and used at home and abroad The continuous equipment is suitable for the production of products with single variety, large output and sufficient raw materials, especially for the production of slurry and granular products Continuous equipment is easy to realize automatic control and simplify manual operation and management Its main disadvantage is high cost With the end of GMP certification, the domestic freeze-drying equipment for medicine has entered the modern stage, with complete functions, reliable work and stable performance It can realize CIP or sip, and all technical indexes can meet the needs of biological products and medicine freeze-drying production In contrast, there are more varieties and specifications of freeze-drying equipment in foreign countries than in China, with complete supporting equipment, delicate energy-saving structure, and large production capacity of continuous freeze-drying equipment In order to ensure the quality and energy saving of freeze-dried products, the combined lyophilization equipment, such as spray freeze drying equipment, is often combined with freeze-drying equipment and other drying equipment Experts of air conditioning refrigeration market foresee that in the near future, how to improve the efficiency of freeze-drying, shorten the drying time and save energy on the premise of ensuring the quality of products will be the goal of the freeze-drying industry workers.