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Application of real-time live cell analysis in hepatocellular carcinoma (HCC) research

 Last Update: 2022-08-30
 Source: Internet
 Author: User

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Case Study

Nature Inducing and exploiting vulnerabilities for the treatment of liver cancer Incucyte® Real-Time Live Cell Imaging System

CDC7 is a target of senescence-inducing strategies in liver cancer

Figure 1 Two-step screening identifies CDC7 as a target for senescence-inducing strategies in liver cancer

Inhibition of CDC7 selectively induces senescence in hepatoma cells with TP53 mutations

Figure 2 Clone formation in different cell lines after adding increasing concentrations of XL413

mTOR inhibitor promotes XL413-induced apoptosis in senescent hepatoma cells

Combination of XL413 and AZD8005 inhibits tumor growth in vivo

SummaryExploiting induced vulnerability may be an effective treatment for liver cancerDownload

Download the Chinese white paper
"Top 10 Applications of Live Cell Analysis in Immunology" to learn aboutthe application highlights of
Incucyte® in immunology and cancer analysis

Scan the QR code to download now

-References-
[1] Wenxin Qin, Leila Akkari & René Bernards.
Inducing and exploiting vulnerabilities for the
treatment of liver cancer.
Nature.
https://doi.
org/10.
1038/s41586-019-1607-3

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