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    Home > Active Ingredient News > Drugs Articles > Application of two-stage reverse osmosis process for purified water

    Application of two-stage reverse osmosis process for purified water

    • Last Update: 2014-04-11
    • Source: Internet
    • Author: User
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    The application of the two-stage reverse osmosis water treatment process is a new type of water treatment technology, which is at the first level in the world It has a broad application prospect in the pharmaceutical production, especially in the GMP transformation of enterprises This process can not only ensure that the treated water can meet the standard of purified water stipulated in Pharmacopoeia, but also avoid the environmental pollution caused by traditional process, and effectively reduce the cost of water treatment Water is an indispensable raw material in pharmaceutical production In the production of tablet, capsule, oral liquid and external medicine, all the equipment, containers, inner packages and tools in contact with the medicine shall be cleaned with pure water; in the production of sterile preparation, all the containers, inner packages and tools in contact with the medicine shall be cleaned with distilled water; in the production of large infusion and injection, a large amount of distilled water is needed Whether water treatment process and equipment are advanced or not is directly related to the quality and cost of drug production For many years, the traditional process of pharmaceutical enterprises in China can not be separated from ion exchange The regeneration of ion exchange must use acid and alkali, equipped with acid and alkali storage tanks and neutralization tanks, which not only causes environmental pollution, but also increases the investment in equipment Reverse osmosis is one of the effective water treatment methods of Zui in modern science and technology Its principle is that when the same volume of dilute solution (such as fresh water) and concentrated solution (such as sea water or salt water) are placed on both sides of the same container, and the middle is blocked by a semi permeable membrane, the solvent in the dilute solution will naturally flow through the semi permeable membrane to the side of the concentrated solution, so that the liquid level on the side of the concentrated solution is higher than that on the side of the dilute solution When the surface is higher than a certain height, a pressure difference is formed to reach the osmotic equilibrium state This pressure is the osmotic pressure (the size of the osmotic pressure depends on the type of concentrated solution) If a pressure greater than the osmotic pressure is applied on one side of the concentrated solution, the solvent in the concentrated solution will flow to the dilute solution, and the flow direction is exactly opposite to the original osmotic direction, which is called reverse osmosis Reverse osmosis is a membrane separation technology driven by pressure When the pressure applied in the water treatment system is greater than the osmotic pressure of the aqueous solution, the water molecules will continuously penetrate the membrane, passing through the membrane The water production channel flows into the central pipe, and then flows out from the outlet end The impurities such as ions, organics and bacteria in the water will be intercepted at the inlet side of the membrane and flow out from the outlet end of the concentrated water, so as to achieve the purpose of separation and purification In the process of water treatment, reverse osmosis must be used twice The brief process is as follows: first, the raw water is sent to the raw water tank through the pipeline, and the raw water is pressurized into the mechanical filter; between the raw water and the mechanical filter, the chemical metering pump is used to inject flocculant, further coagulate the suspended solids in the water and filter through the mechanical filter; then, the residual chlorine and organic matters in the water are further removed through the active carbon filter, so that the pretreatment water can reach the qualified standard 。 Before the qualified pretreatment enters the RO, the scale inhibitor shall be injected by the chemical metering pump to prevent the RO membrane from scaling, and then enter the primary RO device after being pressurized by the high-pressure pump through the security filter; the produced water from the primary RO device enters the intermediate water tank, and then enters the secondary RO device after adjusting the pH value, and the produced water from the secondary RO treatment enters the produced water After the tank is filtered by the terminal, it will become qualified purified water, which can be directly delivered to each water point, and can also enter the distilled water mechanism to prepare distilled water Compared with the traditional water treatment process, the two-stage reverse osmosis process does not need ion exchange, acid and alkali required for ion exchange regeneration, acid and alkali storage tank and neutralization tank, so as to effectively avoid environmental pollution caused by the use of the traditional process and reduce the cost of equipment In addition, the two-stage reverse osmosis process can completely remove colloidal substances, organic matters, iron ions and silicon dioxide that are difficult to be removed by the traditional process; improve the adaptability of water treatment equipment to the change of raw water quality and the reliability of effluent water quality; improve the automation degree and technical content of water treatment system; reduce the labor intensity of operators, etc In recent two years, the secondary reverse osmosis process has been favored by many pharmaceutical enterprises The company has designed and installed the secondary reverse osmosis water treatment system for dozens of pharmaceutical enterprises, many of which have passed GMP certification.
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