ARCH PATHOL LAB MED: A comparison of high-throughput automatic immunoassomeanalyzers for detection of HBV infection

High-throughput automated immunoassay analyzers with high-throughput serological markers of hepatitis B virus have been introduced, but have not yet been compared with existing systemsThis study compared the analysis of hepatitis B surface antigens, hepatitis B surface antibodies, and total core antibodies of hepatitis B between the Architect i2000 platform and the updated high-throughput fully automatic immunoassay analyzerfrom May 2018 to June 2018, a total of 932, 914 and 1055 samples were tested at the research center using the Architect i2000 system for routine testing of hepatitis B surface antigens, hepatitis B surface antibodies and total hepatitis B core antibodies, re-use alinity i, Atellica IM, and Cobas e801 systemsresults showed that the total system compliance rates of hepatitis B surface antigen, hepatitis B surface antibody and hepatitis B core antibody were 98.0%, 89.5% and 93.0%, respectivelyCohen's value is more than 0.8The correlation between the surface antibodies levels of serum hepatitis B, as measured by the four systems, was higher (r s 0.85)The average surface antibody for hepatitis B is greater than Architect i2000 (PAlinity i, Atellica IM and Cobas e801 autoimmune analyzers perform well in detecting HBV infection compared to existing Architect i2000 systemsHowever, the new system has a higher titer and positive rate of hepatitis B surface antibodies and is more sensitiveIt is important to note that the total positive rate of hepatitis B core antibodies in Atellica IM is lower than that of Architect i2000