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    Home > Active Ingredient News > Immunology News > ARD: Use of TNF inhibitors in children with juvenile idiopathic arthritis increases psoriasis incidence

    ARD: Use of TNF inhibitors in children with juvenile idiopathic arthritis increases psoriasis incidence

    • Last Update: 2022-05-22
    • Source: Internet
    • Author: User
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    Objectives : Psoriasis has been documented in pediatric patients following the use of tumor necrosis factor (TNF) inhibitors (TNFi) , but the association of TNFi with psoriasis in juvenile idiopathic arthritis (JIA) has not been as strong as in children As evidenced by large prospective clinical observations such as the Arthritis and Rheumatology Research Consortium


    Objectives : Psoriasis has been documented in pediatric patients following the use of tumor necrosis factor (TNF) inhibitors (TNFi) , but the association of TNFi with psoriasis in juvenile idiopathic arthritis (JIA) has not been as strong as in children As evidenced by large prospective clinical observations such as the Arthritis and Rheumatology Research Consortium


    Methods: De-identified data were obtained from the CARRA registry


    Results: A total of 8225 patients were included, and the median follow-up time was 3.


    Conclusions: In a large prospective registry of patients with JIA , we observed a nearly three-fold increase in psoriasis risk following TNFi exposure .


    Conclusions: In a large prospective registry of patients with JIA , we observed a nearly three-fold increase in psoriasis risk following TNFi exposure .


    Source: Zhao Y, Sullivan E, Son MB , et al .
    Psoriasis rate is increased by the exposure to TNF inhibition in children with JIA.
    Annals of the Rheumatic Diseases2022; 81: 662-665.
    , et al Annals of the Rheumatic Diseases  81:

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