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▎The content team editor of WuXi AppTec.
There are thousands of microorganisms living in the human intestines.
They are not only diverse in species, but also huge in number, with hundreds of billions.
While relying on the intestines to survive, they are also involved in important systems of the human body.
Physiological functions, such as immune system function.
As one of the largest immune organs in the human body, about 70% of the immune system is located in the intestine.
The type and quantity of intestinal microorganisms (called the microbiome) directly affect the balance of intestinal inflammation.
When the intestinal microbiome is in a balanced and healthy state, it helps to maintain and enhance immunity and resist inflammation; if it is in an unbalanced state, it may trigger and aggravate inflammation and increase the risk of various inflammation-related diseases, such as Diabetes, arthritis, heart disease and systemic lupus erythematosus, etc.
Daily diet, while meeting human nutrition and energy requirements, also affects the intestinal microbiome, affecting their types and numbers.
Which foods will affect the microbiome related to intestinal inflammation and have anti-inflammatory or pro-inflammatory effects? Image source: 123RF Recently, a study published in the Gut (GUT) showed that diets rich in animal foods, processed foods, alcohol and sugar are related to the increase in the number of pro-inflammatory microorganisms; A plant-based diet is related to the increase in the number of anti-inflammatory microorganisms.
Researchers from the University of Groningen in the Netherlands conducted a follow-up study of 1,425 subjects, 41% of whom were men.
To evaluate the influence of diet on the gut microbiome of different populations, 124 of the subjects had ulcerative colitis (UC), 205 had Crohn’s disease (CD), and 223 had irritable bowel syndrome.
(IBS), 872 people are healthy people without intestinal diseases.Through the questionnaire, the researchers collected the subjects’ age, gender, height, weight, smoking status, use of antihypertensive and hypoglycemic drugs, as well as the frequency and quantity of different foods consumed in the last month, including alcohol and meat.
There are 173 kinds of foods, such as vegetables, bread, vegetables, fruits, nuts, dairy products, fish and non-alcoholic beverages.
In addition, the researchers also collected stool samples from the subjects to measure the levels of inflammation markers and analyze the intestinal flora.
Image source: 123RF After adjusting for the influence of other factors, the researchers found that a variety of foods have an impact on the gut microbiome, and these effects are similar in different populations.
Processed foods and animal foods are always related to the relatively high number of opportunistic pathogens, including certain bacteria belonging to Firmicutes and Ruminococcus, and these gut microbes can promote inflammation effect.
Opportunistic pathogens refer to the breakdown of the balance of the intestinal microbiome, and the non-pathogenic bacteria in the original normal flora can be transformed into pathogenic bacteria.
Plant foods and fish are associated with an increase in the abundance of the intestinal microbiome that has anti-inflammatory effects.
For example, the increase in the consumption of fruits and deep-sea fish is related to the increase in the abundance of Faecalibacterium prausnitzii; the increase in the intake of nuts, deep-sea fish, vegetables, whole grains and legumes is related to the increase in the intake of (Roseburia, hominis) is associated with increased abundance.
These intestinal microbiomes not only have anti-inflammatory effects, but also protect the intestinal mucosa and cells by fermenting dietary fiber and pectin into acetate and butyrate.
The consumption of sugary foods, including sugary beverages, candies, etc.
, is related to the decrease in the abundance of Clostridium prasici.
Drinking coffee is related to the increase in relative abundance of Oscillibacter; while eating fermented dairy products (such as buttermilk and yogurt) is related to the abundance of Bifidobacterium, Lactobacillus and Enterococcus Increase is closely related.
These gut microbiomes also have anti-inflammatory effects.
In addition, the researchers also found that eating fast foods such as meat, French fries, mayonnaise, and soft drinks is related to the increase in the abundance of some "unfriendly" gut microbiomes, including Clostridium bolteae, feces Coprobacillus and Lachnospiraceae.
The researchers pointed out that in the absence of dietary fiber, these bacteria will enter the mucus layer of the intestinal tract, causing the integrity of the intestinal tract to be eroded.
Image source: 123RF Since this study is an observational study, it only shows the association between different foods and the gut microbiome, and does not indicate a causal relationship.
Moreover, the time required for the gut microbiome to respond to diet is currently uncertain, which is also a limitation of the study.
However, the researchers pointed out that despite the limitations of the study, it is certain that certain foods will affect the anti-inflammatory microbiome in the intestine, thereby protecting the mucosa, reducing inflammation, and promoting health.
Researchers suggest that whether it is healthy people, or patients with ulcerative colitis, Crohn's disease, and irritable bowel syndrome, increase the consumption of beans, vegetables, fruits, and nuts in their daily diet to make plant-based foods account for Exceed animal food; at the same time, increase low-fat fermented dairy products and fish in an appropriate amount, avoid drinking alcohol, reduce the consumption of processed foods and sugary beverages, and stick to it for a long time to promote the growth of the anti-inflammatory microbiome in the intestinal tract, and improve the intestinal and Overall health, reducing the risk of inflammation-related diseases.
Recommended reading Authoritative release: In 2040, China’s new cancer cases will reach 6.
85 million, and deaths will reach 5.
07 million.
Warm spring is approaching, 6 types of diet "magic weapons" make immunity add to your health 50% of people who don’t know they are sick For the evaluation and prevention of this disease, it is necessary to understand what will happen to the incidence and death of cancer after 20 years? There are two points to determine that 66% of diabetic patients die because of this type of disease! How to prevent reference materials[1] Laura A Bolte, et al.
,(2021).
Long-term dietary patterns are associated with pro-inflammatory and anti-inflammatory features of the gut microbiome.
Gut, DOI: http://dx .
doi.
org/10.
1136/gutjnl-2020-322670.
[2] Diet rich in animal foods, alcohol and sugar linked to'inflammatory' gut microbiome.
Retrieved Apr 15 ,2021,from https://medicalxpress.
com/news/ 2021-04-diet-rich-animal-foods-alcohol.
html Note: This article aims to introduce the progress of medical and health research, not a treatment plan recommendation.
If you need guidance on treatment plans, please go to a regular hospital for treatment.
There are thousands of microorganisms living in the human intestines.
They are not only diverse in species, but also huge in number, with hundreds of billions.
While relying on the intestines to survive, they are also involved in important systems of the human body.
Physiological functions, such as immune system function.
As one of the largest immune organs in the human body, about 70% of the immune system is located in the intestine.
The type and quantity of intestinal microorganisms (called the microbiome) directly affect the balance of intestinal inflammation.
When the intestinal microbiome is in a balanced and healthy state, it helps to maintain and enhance immunity and resist inflammation; if it is in an unbalanced state, it may trigger and aggravate inflammation and increase the risk of various inflammation-related diseases, such as Diabetes, arthritis, heart disease and systemic lupus erythematosus, etc.
Daily diet, while meeting human nutrition and energy requirements, also affects the intestinal microbiome, affecting their types and numbers.
Which foods will affect the microbiome related to intestinal inflammation and have anti-inflammatory or pro-inflammatory effects? Image source: 123RF Recently, a study published in the Gut (GUT) showed that diets rich in animal foods, processed foods, alcohol and sugar are related to the increase in the number of pro-inflammatory microorganisms; A plant-based diet is related to the increase in the number of anti-inflammatory microorganisms.
Researchers from the University of Groningen in the Netherlands conducted a follow-up study of 1,425 subjects, 41% of whom were men.
To evaluate the influence of diet on the gut microbiome of different populations, 124 of the subjects had ulcerative colitis (UC), 205 had Crohn’s disease (CD), and 223 had irritable bowel syndrome.
(IBS), 872 people are healthy people without intestinal diseases.Through the questionnaire, the researchers collected the subjects’ age, gender, height, weight, smoking status, use of antihypertensive and hypoglycemic drugs, as well as the frequency and quantity of different foods consumed in the last month, including alcohol and meat.
There are 173 kinds of foods, such as vegetables, bread, vegetables, fruits, nuts, dairy products, fish and non-alcoholic beverages.
In addition, the researchers also collected stool samples from the subjects to measure the levels of inflammation markers and analyze the intestinal flora.
Image source: 123RF After adjusting for the influence of other factors, the researchers found that a variety of foods have an impact on the gut microbiome, and these effects are similar in different populations.
Processed foods and animal foods are always related to the relatively high number of opportunistic pathogens, including certain bacteria belonging to Firmicutes and Ruminococcus, and these gut microbes can promote inflammation effect.
Opportunistic pathogens refer to the breakdown of the balance of the intestinal microbiome, and the non-pathogenic bacteria in the original normal flora can be transformed into pathogenic bacteria.
Plant foods and fish are associated with an increase in the abundance of the intestinal microbiome that has anti-inflammatory effects.
For example, the increase in the consumption of fruits and deep-sea fish is related to the increase in the abundance of Faecalibacterium prausnitzii; the increase in the intake of nuts, deep-sea fish, vegetables, whole grains and legumes is related to the increase in the intake of (Roseburia, hominis) is associated with increased abundance.
These intestinal microbiomes not only have anti-inflammatory effects, but also protect the intestinal mucosa and cells by fermenting dietary fiber and pectin into acetate and butyrate.
The consumption of sugary foods, including sugary beverages, candies, etc.
, is related to the decrease in the abundance of Clostridium prasici.
Drinking coffee is related to the increase in relative abundance of Oscillibacter; while eating fermented dairy products (such as buttermilk and yogurt) is related to the abundance of Bifidobacterium, Lactobacillus and Enterococcus Increase is closely related.
These gut microbiomes also have anti-inflammatory effects.
In addition, the researchers also found that eating fast foods such as meat, French fries, mayonnaise, and soft drinks is related to the increase in the abundance of some "unfriendly" gut microbiomes, including Clostridium bolteae, feces Coprobacillus and Lachnospiraceae.
The researchers pointed out that in the absence of dietary fiber, these bacteria will enter the mucus layer of the intestinal tract, causing the integrity of the intestinal tract to be eroded.
Image source: 123RF Since this study is an observational study, it only shows the association between different foods and the gut microbiome, and does not indicate a causal relationship.
Moreover, the time required for the gut microbiome to respond to diet is currently uncertain, which is also a limitation of the study.
However, the researchers pointed out that despite the limitations of the study, it is certain that certain foods will affect the anti-inflammatory microbiome in the intestine, thereby protecting the mucosa, reducing inflammation, and promoting health.
Researchers suggest that whether it is healthy people, or patients with ulcerative colitis, Crohn's disease, and irritable bowel syndrome, increase the consumption of beans, vegetables, fruits, and nuts in their daily diet to make plant-based foods account for Exceed animal food; at the same time, increase low-fat fermented dairy products and fish in an appropriate amount, avoid drinking alcohol, reduce the consumption of processed foods and sugary beverages, and stick to it for a long time to promote the growth of the anti-inflammatory microbiome in the intestinal tract, and improve the intestinal and Overall health, reducing the risk of inflammation-related diseases.
Recommended reading Authoritative release: In 2040, China’s new cancer cases will reach 6.
85 million, and deaths will reach 5.
07 million.
Warm spring is approaching, 6 types of diet "magic weapons" make immunity add to your health 50% of people who don’t know they are sick For the evaluation and prevention of this disease, it is necessary to understand what will happen to the incidence and death of cancer after 20 years? There are two points to determine that 66% of diabetic patients die because of this type of disease! How to prevent reference materials[1] Laura A Bolte, et al.
,(2021).
Long-term dietary patterns are associated with pro-inflammatory and anti-inflammatory features of the gut microbiome.
Gut, DOI: http://dx .
doi.
org/10.
1136/gutjnl-2020-322670.
[2] Diet rich in animal foods, alcohol and sugar linked to'inflammatory' gut microbiome.
Retrieved Apr 15 ,2021,from https://medicalxpress.
com/news/ 2021-04-diet-rich-animal-foods-alcohol.
html Note: This article aims to introduce the progress of medical and health research, not a treatment plan recommendation.
If you need guidance on treatment plans, please go to a regular hospital for treatment.
