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Are women with diabetes at higher risk of venous thromboembolism than men? But it has attracted attention...

 Last Update: 2023-02-03
 Source: Internet
 Author: User

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Physicians should intensively treat
all risk factors when the patient is younger.

Executive Summary

On January 3, 2023, a study published in Diabetes Research and Clinical Practice showed that women with diabetes had a higher risk of venous thromboembolism than men
.

Study screenshots

status quo

Carola Deischinger, MD, Department of Endocrinology and Metabolism, Medical University of Vienna, said:

Type 2 diabetes is a chronic blood sugar disorder that affects more than 8% of the global population and is associated
with a variety of microvascular and macrovascular complications.
The risk of developing venous thromboembolism (VTE) is equal in both sexes
.
Studies have shown that diabetes mellitus (DM) is a risk factor for pulmonary embolism and deep vein thrombosis, but the sex-specific effect of DM on VTE is unclear
.

conclusion

The investigators collected medical data from a retrospective population-level cohort study in Austria from 1997 to 2014, from which 180034 patients with DM were sampled and compared
with 540102 gender- and age-matched patients without DM.

The results show:

Patients with DM had a 1.
4-fold greater risk of VTE than control (95% CI: 1.
36-1.
43, p < 0.
001).
The association of DM with newly diagnosed VTE was significantly greater in women (OR = 1.
52, 95% CI: 1.
46 to 1.
58, p < 0.
001), and across all age groups, the relative risk of VTE increased 1.
17-fold in women with DM compared with men with DM, peaking between 50 and 59 years [1.
65 (95% CI 1.
43 to 1.
89)].

prospect

Alexandra Kautzky-Willer, MD of the Medical University of Vienna, said:

Our findings suggest that women with diabetes should be more carefully monitored for VTE, particularly during their perimenopausal period
.
This result also suggests that as estrogen levels decline during menopause, a woman's risk increases further
.
Physicians should intensively treat
all risk factors when the patient is younger.

Elma Dervic of the Department of Complex Systems Science at the Medical University of Vienna said:

To study this sex-specific correlation between DM and VTE, the reasons for
the increased risk need to be analyzed.
This will be an important step
in preventing VTE in DM patients.

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