echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Immunology News > Arthritis Rheumatol: Effects of vitamin D and Omega-3 fatty acids on chronic knee pain

    Arthritis Rheumatol: Effects of vitamin D and Omega-3 fatty acids on chronic knee pain

    • Last Update: 2020-07-13
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com


    Knee pain caused by osteoarthritis is common in adults

    Previous trials have had inconsistent results in

    vitamin D

    on knee pain treatment, and few have studied marine omega-3 fatty acids (n-3 FA)



    the two-blind, placebo-controlled trial (VITAL) on vitamin D and Omega-3 randomly divided 25,871 U.S

    adults into vitamin D and n-3 FA treatment groups using a two-factor design

    A subgroup of chronic knee pain was identified prior to the random grouping and the arthritis index (WOMAC; 0-100, 100 worst) was assessed annually at the baseline and follow-up during the baseline and follow-up period

    After adjusting age and gender, the repeated measurement model verified the effect of random izedness treatment on WOMAC pain during follow-up

    The WOMAC function and joint stiffness repeat are analyzed



    included 1,398 participants who returned at least one knee pain questionnaire

    THE AVERAGE AGE IS 67.7 YEARS, 66% FEMALE, AND THE AVERAGE WOMAC PAIN IS 37 (SD 19)

    The average follow-up time was 5.3 years (SD 0.7)

    There was no difference between the vitamin D or n-3 FA group and the WOMAC pain in the placebo group at any point in the follow-up period

    The interaction time between the two treatments was not statistically significant (vitamin D p-0.41, n-3 FA p-0.77)

    Over time, vitamin D supplementation and n-3 FA supplementation did not significantly affect WOMAC function or stiffness scores

    in a large sample of adult patients with chronic knee pain, the average vitamin D and n-3 fatty acid supplements for 5.3 years did not reduce knee pain or improve function or joint stiffness

    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent Echemi's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.