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Arthritis Rheumatol: Efficacy, safety and pharmacodynamic effects of Bruton's tyrosine kinase inhibitor Fenebrutinib in the treatment of systemic lupus erythematosus

 Last Update: 2022-04-17
 Source: Internet
 Author: User

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Figure 1: Changes in plasma blast gene signatures in patients with systemic lupus erythematosus treated with placebo, fenebrutinib 150 mg once daily (Qd), or fenebrutinib 200 mg twice daily (Bid)

Figure 2.

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Source:Isenberg D, Furie R, Jones NS, Efficacy, Safety, and Pharmacodynamic Effects of the Bruton's Tyrosine Kinase Inhibitor Fenebrutinib (GDC-0853) in Systemic Lupus Erythematosus: Results of a Phase II, Randomized, Double-Blind, Placebo- Controlled Trial.

Isenberg D, Furie R, Jones NS, Efficacy, Safety, and Pharmacodynamic Effects of the Bruton's Tyrosine Kinase Inhibitor Fenebrutinib (GDC-0853) in Systemic Lupus Erythematosus: Results of a Phase II, Randomized, Double-Blind, Placebo-Controlled Trial.

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