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    Home > Biochemistry News > Biotechnology News > Artificial Radical Generating and Scavenging Systems: Photo-Fenton Reagent and Caged Compounds

    Artificial Radical Generating and Scavenging Systems: Photo-Fenton Reagent and Caged Compounds

    • Last Update: 2020-12-24
    • Source: Internet
    • Author: User
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    A photo-labile compound that is bioinactive but upon irradiation with light yields bioactive species, is called as “caged compound” (
    1
    ) (
    see
    Scheme 1). Photolysis of caged compounds generating bioactive species, i.e., “uncaging,” has become a general method to produce a desired amount of bioactive species in a specific time interval at desired place or area of the target biological systems (
    1
    ,
    2
    ). This chapter deals with two caged free radicals: a caged hydroxyl radical, i.e., photo-Fenton reagent, and caged nitric oxides (NOs). Uncaging of these caged free radicals yield hydroxyl radical and NO, respectively, which are believed to be associated with free-radical tissue damage.
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