Artificial sweeteners can aggravate inflammation in patients with Crohn's disease

Proteus includes a large number of different types of bacteria, such as Escherichia coli, Salmonella, etc Most of these bacteria are normal in the body and do not have pathogenicity Most Proteus bacteria have cell walls made up of LPS, which can induce strong immune and inflammatory reactions Crohn's disease is a kind of gastroenteritis, which occurs in the digestive tract Patients often have abnormal pain, severe diarrhea, bloody stool, weight loss and fatigue According to the report, 10% to 15% of patients said sweeteners would aggravate their condition Recently, published in the latest issue of the journal infectious bowel diseases, researchers from the University of Case Western Reserve found that an artificial sweetener called "good taste sugar" can aggravate the inflammatory response of mice with Crohn's disease The results showed that the number of microorganisms in the gut called Proteus increased significantly after drinking water containing good taste sugar Half of the mice tested had Crohn's disease, while the other half were healthy (http:// Compared with the healthy group, the disease of mice in the disease group showed a significant deterioration after drinking water, and the penetration of bacteria to the intestinal wall was also significantly improved The researchers also found that the intake of good sugars led to an increase in intestinal myeloperoxidase activity in mice with the disease The enzyme is secreted by leukocytes and can kill a variety of microorganisms This phenomenon indicates that the immune response of the body against microorganisms has occurred These results suggest that the intake of good sugars will increase the activity of myeloperoxidase in the affected individuals, such as Crohn's disease or other enteritis In this process, inflammatory reaction and corresponding accompanying symptoms will aggravate the condition of enteritis This research shows that the artificial sweetener, called "good taste sugar", can cause the aggravation of enteritis, so people with enteritis should be cautious about eating foods containing the substance.