Astragaloside IV

Astragaloside IV

Astragaloside Ⅳ

【Structural formula】

[Molecular formula and molecular weight] C ₄₁ H ₆₈ O ₁₄ ; 784.

[Source] The dried root of legume Astragalus membranaceus (Fisch.

【Properties】White powder

This product is soluble in water and dilute alcohol, but almost insoluble in ether and benzene

Melting point: 295～296℃

【Purity Check】

TLC

1.

Developing solvent of chloroform - methanol - water (65:35:10) the lower layer liquid

After checking the color development of 10% sulfuric acid ethanol solution, check under sunlight and ultraviolet light (365nm)

2.

Developing agent chloroform- ethyl acetate - methanol -water (15:40:22:10) lower layer

After checking the color development of 10% sulfuric acid ethanol solution, check under sunlight and ultraviolet light (365nm)

High performance liquid chromatography

Column Phenomenex Gemini C ₁₈ , 5um(4.

Mobile phase acetonitrile-water (30:70), 1ml/min

ELSD2000 evaporative light scattering detection nitrogen flow rate, 2.

【Structural identification】202

3406(-OH), 2939, 1635, 1457, 1378, 1367, 1157, 1078, 1046, 992, 895

FAB-MS m/z: 807[M+Na] ⁺ , 785[M+H] ⁺

¹ H-NMR (C ₅ D ₅ N) δ: 0.

¹³ C-NMR (C ₅ D ₅ N) δ: 29.

【Storage】Dry and airtight