Author: meilin

However, the fact is that the risk of developing cardiovascular disease in diabetic patients is 2-4 times higher than that in normoglycemic people [1], and cardiovascular disease is the leading cause of death in diabetic patients
.

It should be noted that patients with diabetes are often accompanied by important risk factors for cardiovascular diseases such as hypertension and dyslipidemia.
Under the synergistic effect of the three, the risk of occurrence and progression of macrovascular and microvascular complications of diabetes is significantly increased, and it also increases the risk of patients with diabetes.

It is currently in the early spring season, and it is warm and cold, and the temperature difference between morning and evening is relatively large
.

Temperature changes will have a certain impact on the contraction and relaxation of blood vessels, resulting in large fluctuations in blood pressure, and may even induce acute cardiovascular and cerebrovascular events such as angina pectoris or myocardial infarction

Therefore, in the process of hypoglycemic treatment, Sangao diabetics should not only actively screen and control cardiovascular disease risk factors, but also give priority to hypoglycemic drugs that have a protective effect on cardiovascular disease
.

The "Chinese Guidelines for the Prevention and Treatment of Type 2 Diabetes (2020)" pointed out in the "Treatment Pathway for Type 2 Diabetes" that "type 2 diabetes patients with atherosclerotic cardiovascular disease (ASCVD) or high risk of cardiovascular risk, regardless of their HbA 1c Whether the target is met, as long as there is no contraindication, GLP-1RA (glucagon-like peptide-1 receptor agonist) or SGLT2i (sodium-glucose cotransporter 2 inhibitor) with evidence of ASCVD benefit should be added to metformin agent)
.

(A)” [1]

Some sugar friends may ask: Why add GLP-1RA or SGLT2i on the basis of metformin? Can I use GLP-1RA or SGLT2i alone? Corresponding explanations are also given in the Guide
.

First of all, metformin is the most commonly used hypoglycemic drug at present, with good hypoglycemic effect and potential benefits other than various hypoglycemic effects, superior cost-effectiveness ratio, good drug accessibility, rich clinical experience and other advantages, and Does not increase the risk of hypoglycemia

In addition, the early spring season is also the season when the flu and the new crown epidemic are prone to comeback.
Sugar lovers should still go out as little as possible to reduce the risk of infection
.

Therefore, it is recommended that people with diabetes can choose large packages of metformin; or buy them at a nearby regular pharmacy to reduce the number of visits to the hospital

Drawing: Aliao

Produced by: "Chinese Family Doctor" magazine

Academic Advisor: Zhou Lin

Deputy Chief Physician, Associate Professor, Postgraduate Supervisor, Department of Endocrinology, Southern Hospital

Deputy Chairman of the Professional Committee of Thyroid Diseases of Guangdong Health Management Association

Member of Diabetes Branch of Guangdong Medical Association, Deputy Head of Pregnancy Endocrinology Professional Group of Endocrinologist Branch

Member of the Professional Committee of Wound Treatment of Guangdong Association of Integrative Chinese and Western Medicine

references:

1.

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