Because cancer cells don’t understand "economics", scientists have found a way to kill them easily

In 1981, Nobel Prize economist Professor James Tobin gave the famous advice: "Don't put all your eggs in the same basket.

However, scientists have recently discovered that strong-growing cancer cells may not understand this truth, and will "put all the eggs in one basket", do not prepare Plan B at all, and only rely on a molecular pathway to repair their DNA.

Professor Christopher Vakoc of the Cold Spring Harbor Laboratory focuses on cancer research and wants to find out whether cancer cells have unique dependencies, that is, whether their survival depends on certain unique molecular mechanisms.

Recently, this research team published a paper in Cancer Discovery under the American Association for Cancer Research (AACR).

In normal cells, a special type of DNA damage can be repaired in two different ways: ALDH2 gene and Fanconi anemia (FA) signaling pathway.

The researchers explained that in order to grow and spread quickly, cancer cells may inadvertently remove multiple repair methods in the process of DNA mutation.

Note: The original text has been deleted

Reference materials:

[1] Zhaolin Yang et al.

[2] When cancer cells "put all their eggs in one basket".