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A current study involves biodegradable polymer composite coatings deposited by laser technology for biodegradable medical applications.
scientists reported on biopolymer composite coating deposition for medical applications, requiring adjustable biodegradability, matrix-assisted pulsed laser evaporation through sterile laser tool technology, test degradation, wetting and bio-compatibility preservation.
specific FTIR bands of the two materials indicate the chemical measurement deposition of the composite coating, and also indicate the main presence of amorphotic SF phase, which is also confirmed by XRD to have a low-strength maximum
. With regard to PSADT composition, XRD clearly demonstrates its specific crystallization contribution.
degradation trend is slower
studied the degradation behavior of simulated body fluids at 37 degrees C in a dynamic state as a first step in the applicability of potential continuous control release applications (and/or biodegradable implantable electronics). With the increase in the initial PSADT volume, weighing measurements of degraded samples confirm a slower degradation trend. They also show approximate zero-level SBF degradation of the 1:1 SF-PSADT ratio. In-body measurements showed that human-filled stem cells spread evenly across all synthetic coatings.
the study was published in Organic Coatings Progress Volume 134, September 2019, pp. 11-21.