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Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the formation of pathogenic autoantibodies and immune complexes that mediate organ and tissue damage, often involving multiple systems in clinical practice
.
In addition, lupus nephritis (LN) is a common and serious complication, more than 50% of patients have clinical manifestations of renal impairment, and biopsy-proven lupus nephritis occurs in 20-40% of patients, usually at least Appeared for more than 3 years
Lupus nephritis (LN) is a common and serious complication, more than 50% of patients have clinical manifestations of renal impairment, biopsy-proven lupus nephritis occurs in 20-40% of patients, usually at least 3 years or more
At present, the treatment of lupus nephritis is mainly based on glucocorticoids and immunosuppressive agents
The pathogenesis of lupus nephritis and the mechanism of action of various traditional Chinese medicines:
The main components and mechanism of action of single traditional Chinese medicine:
The main components and mechanism of action of single traditional Chinese medicine:Active ingredients and mechanism of action of natural extracts of traditional Chinese medicine:
Active ingredients and mechanism of action of natural extracts of traditional Chinese medicine:The composition and mechanism of action of traditional Chinese medicine:
The composition and mechanism of action of traditional Chinese medicine:The pathogenesis of LN is complex.
Although it is clear that glucocorticoids combined with immunosuppressive therapy are widely used, the overall efficacy is not optimistic
.
However, the application of traditional Chinese medicine, natural extracts can greatly improve the occurrence and severity of side effects of western medicine, and can have various pharmacological effects, such as reducing the deposition of antibodies and immune complexes, reducing the production of inflammatory mediators, thereby preventing further progression, and Improve existing kidney damage
The application of traditional Chinese medicine, natural extracts can greatly improve the occurrence and severity of side effects of western medicine, and can have a variety of pharmacological effects, such as reducing the deposition of antibodies and immune complexes, reducing the production of inflammatory mediators, thereby preventing further progress, and improving the present.
Future research should explore the value of traditional Chinese medicine and natural substance extracts, and at the same time accurately and reasonably understand the toxicity of traditional Chinese medicine, so as to provide a good basis for clinical practice
Original text: Wang YJ, Li YX, Li S, He W, Wang ZR, Zhan TP, Lv CY, Liu YP, Yang Y, Zeng XX.
Progress in traditional Chinese medicine and natural extracts for the treatment of lupus nephritis.
Biomed Pharmacother.
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