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Blood: Bentuximab combined with nivolumab in the treatment of relapsed or refractory Hodgkin's lymphoma: results of a 3-year study

 Last Update: 2021-05-08
 Source: Internet
 Author: User

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Recently, a Phase 1-2 study evaluated the effect of Bentuximab (BV) combined with Nivolumab (Nivo) as the first salvage therapy for patients with relapsed or refractory classic Hodgkin’s lymphoma .

Lymphoma

In the first and second parts, the patient received alternate dosing of BV and Nivo in cycle 1, and then on the same day in cycles 2-4.

stem cell

The results showed that the objective response rate (N=91) was 85%, and 67% of patients achieved complete remission.

immunity

In summary, the long-term follow-up results show that BV and Nivo as the first salvage program have shown long-lasting efficacy and long PFS, especially in patients who directly undergo stem cell transplantation, without additional toxicity problems.

Original source:

ncbi.

ncbi.
nlm.
nih.
gov/?term=Advani+R&cauthor_id=33827139">Advani Ranjana ncbi.
nlm.
nih.
gov/33827139/" target="_blank" rel="noopener">Brentuximab vedotin in Combination with nivolumab relapsed or refractory Hodgkin lymphoma in: 3-year Study Results in this message

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