BMC Biol: How much oxygen does the brain need to maintain normal function? Do you know?

July 11, 2020 // The body's brain has a high energy needs and is sensitive to oxygen, and in a recent study published in the international journal BMC Biology, scientists from institutions such as the University of Munich in Germany have directly linked oxygen consumption to the activity of specific nerve cells for the first timepicture source: The energy needed by the H.Straka brain is often not proportional to the body mass, which is produced mainly through an aerobic metabolic process that consumes oxygen, so oxygen concentration in the brain is an important parameter that affects the function of nerve cells and glial cellsthe study, researchers used the study to directly determine the level of oxygen in the complete brain and how it is associated with nerve cell activityin the established animal model, the African claw, the researchers used electrochemical sensors to determine the oxygen concentration of the animal brain and one of the ventricles, which may specifically control the level of oxygen available in the brain and inhibit the activity of nerve cells with the help of pharmacological substances, using nerve cells that control eye movement, and the researchers directly recorded the association between oxygen consumption and nerve cell activity'We found that the brain is oxygen-deprived in a normal air-saturated environment, which means that oxygen cannot be detected, so that full oxygen can be used immediately by cells to synthesize energy-rich substances, and if oxygen is more than twice the atmospheric level, the energy metabolism in brain cells is saturated, which makes the brain abundant,' said Straka, a researcher at theunder normal circumstances, only about 50% of the oxygen will be used for nerve cell activity, while the other 50% of oxygen is needed by glial cells, while maintaining the basic metabolic rate of nerve cells, however, the increased activity of nerve cells tends to consume more oxygenIn order to better understand the mechanism by which information is processed in the brain, researchers need to shed light on the close association between oxygen availability and brain activity, and the results of this paper provide a further study of the energy balance in the brain, and it is important to determine the level of oxygen needed to maintain function of multiple nerve cells, which may also be relevant from a medical point of view, such as helping researchers better understand the consequences of oxygen deficiency in the brain or using imaging techniques to obtain information about the brainoriginal origin s
: Suzan?zugur, Lars Kunz and Hans StrakaRelationship soeom sieoe oedd yn ystod yn ystod, BMC Biology (2020)DOI: 10.1186/s12915-020-00811-6.