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    Home > Active Ingredient News > Antitumor Therapy > BMC Cancer: Durvalumab treatment improves patient outcomes after chemoradiotherapy in locally advanced non-small cell lung cancer (LA-NSCLC)

    BMC Cancer: Durvalumab treatment improves patient outcomes after chemoradiotherapy in locally advanced non-small cell lung cancer (LA-NSCLC)

    • Last Update: 2022-05-18
    • Source: Internet
    • Author: User
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    Recently, a real-world study was published in the journal BMC Cancer to evaluate the effect of durvalumab treatment on the prognosis of patients with locally advanced non-small cell lung cancer (LA-NSCLC) after chemoradiotherapy


    Recently, a real-world study was published in the journal BMC Cancer to evaluate the effect of durvalumab treatment on the prognosis of patients with locally advanced non-small cell lung cancer (LA-NSCLC) after chemoradiotherapy


    Of the 68 patients included in the study, none received induction chemotherapy, and 50 (73.


    Of the 68 patients included in the study, none received induction chemotherapy, and 50 (73.


    During a median follow-up of 14.


    During a median follow-up of 14.


    Multivariate analysis showed that the use of durvalumab significantly reduced the hazard ratio (HR) of DMFS, PFS and OS (HR 0.


    Multivariate analysis showed that the use of durvalumab significantly reduced the hazard ratio (HR) of DMFS, PFS and OS (HR 0.


    There was no significant difference in DMFS, PFS and OS between stage IIIA and IIIB-IIIC (HR = 1.


    There was no significant difference in DMFS, PFS and OS between stage IIIA and IIIB-IIIC (HR = 1.


    Taken together, studies have shown that durvalumab treatment following chemoradiotherapy in locally advanced non-small cell lung cancer (LA-NSCLC) improves patient outcomes


    Original source:

    Original source:

    Yamamoto T, Tsukita Y, Katagiri Y, Matsushita H, Umezawa R, Ishikawa Y, Takahashi N, Suzuki Y, Takeda K, Miyauchi E, Saito R, Katsuta Y, Kadoya N, Jingu K.


    Yamamoto T, Tsukita Y, Katagiri Y, Matsushita H, Umezawa R, Ishikawa Y, Takahashi N, Suzuki Y, Takeda K, Miyauchi E, Saito R, Katsuta Y, Kadoya N, Jingu K.
    Durvalumab after chemoradiotherapy for locally advanced non- small cell lung cancer prolonged distant metastasis-free survival, progression-free survival and overall survival in clinical practice.
    BMC Cancer.
    2022 Apr 4;22(1):364.
    doi: 10.
    1186/s12885-022-09354-1.
    PMID: 35379201.


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