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Hemorrhagic hemorrhagic hemorrhagic ulcers (HGU) are the most common cause of upper gastrointestinal bleeding.
most HGUs can be treated with medication and/or endoscopes.
some HGU patients still have poor prognostics, and in fact, the mortality rate for HGU is still high, at 10%.
another study showed that endoscopic characteristics of the forrester classification (Forrest I, IIa and IIb) with high risk were prognoste indicators of mortality.
in addition to mortality, impaired daily activity capacity (ADL) is also a very important prognosiosal problem, especially in older subjects, which leads to longer hospital stays and higher treatment costs.
currently, hemorrhagic hemorrhagic hemorrhagic intestinal ulcers (HGU) have rarely been studied for damage to daily activity (ADL).
study aims to analyze risk factors for poor prognostication in HGU patients, including mortality and ADL impairment.
reviewed the clinical outcomes of 582 patients diagnosed with HGU.
to enter a nursing facility during hospitalization or need family help is defined as a decline in ADL.
researchers analyzed clinical factors: endoscopic characteristics, whether intervention in endoscopy, combination, symptoms and medication was needed to assess the effects on ADL.
analysis of all risk factors.
study found that old age (75 years old) is an important predictive indicator of poor prognosm, including damage to ADL.
other significant risk factors are kidney disease (OR) 3.43; The 95% confidence interval (CI) 1.44-8.14), the use of proton pump inhibitors (PPI) (OR 5.80; 95% CI 2.08-16.2) and heart disease (OR 3.05; 95% CI 1.11-8.43) before bleeding are all risk factors for adverse prognostication.
analysis of older subjects only showed that the use of PPI before bleeding was an important predictor of ADL damage (OR 8.24; 95% CI 2.36-28.7).
, in addition to older patients, hypothyrosis can also lead to poor prognosis in HGU patients.
, the use of PPI is an important risk factor for ADL damage in overall HGU patients and only in elderly patients.
findings suggest that current strategies for using PPI need to be reconsidered.