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Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal diseases, affecting approximately 10% of the world's population
.
This functional bowel disease can be divided into different categories: diarrhea type (IBS-D), constipation type (IBS-C), mixed type (IBS-M) and unclassified type (IBS-U)
Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal diseases, affecting approximately 10% of the world's population
Recently, it has been proposed to limit fermentable carbohydrates (a low FODMAP diet) in combination with a gluten-free diet (GFD) to reduce the symptoms of patients with irritable bowel syndrome (IBS)
.
Different research reports claim that IBS is related to the dysbiosis of the gut microbiota
In this clinical trial study, 42 patients with IBS received 6 weeks of LF-GFD intervention
.
The IBS Symptom Severity Score (IBS-SSS) was used to assess symptoms, and stool samples were collected at baseline and after the intervention, and quantitative 16 S rRNA PCR was used to determine the diversity of the gut microbiota before and after 6 weeks of dietary intervention
Thirty patients (mean age 37.
8±10.
7 years) in this study completed 6 weeks of diet
.
Compared with baseline, IBS-SSS was significantly reduced after LF-GFD intervention (P=0.
This study showed that the severity of IBS symptoms of IBS patients who received LF-GFD intervention was significantly improved, and their FC levels would also decrease after normalization of the composition of their intestinal microbiota
.
.
Original source:
Kaveh Naseri.
Influence of low FODMAP-gluten free diet on gut microbiota alterations and symptom severity in Iranian patients with irritable bowel syndrome.
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