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    Home > Active Ingredient News > Endocrine System > BMC Med: Effects of oral diabetes medications on glycated hemoglobin (HbA1c) in primary care in Asians

    BMC Med: Effects of oral diabetes medications on glycated hemoglobin (HbA1c) in primary care in Asians

    • Last Update: 2022-03-04
    • Source: Internet
    • Author: User
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    Background: Clinical trials have shown that oral antidiabetic drugs (OADs) can significantly reduce glycated hemoglobin (HbA1c) levels


    Oral antidiabetic drugs (OADs) can significantly reduce glycated hemoglobin (HbA1c) levels


    RESULTS: Among 57,910 patients, 43,338 used OAD at least once, and a total of 76,990 had HbA1c values ​​related to OAD dose


    Table 1 Changes in HbA1c values ​​after using metformin (HbA1c is expressed in mmol/mol)

    Table 1 Changes in HbA1c values ​​after using metformin (HbA1c is expressed in mmol/mol)

    Table 2 Changes in HbA1c values ​​with glipizide (HbA1c expressed in mmol/mol)

    Table 2 Changes in HbA1c values ​​with glipizide (HbA1c expressed in mmol/mol)

    Table 3 Changes in HbA1c values ​​with gliclazide (HbA1c expressed in mmol/mol)

    Table 3 Changes in HbA1c values ​​with gliclazide (HbA1c expressed in mmol/mol)

    Figure 1 Changes of HbA1c (HbA1c expressed in mmol/mol) under different OAD doses


    Figure 1 Changes of HbA1c (HbA1c expressed in mmol/mol) under different OAD doses


    Real-world data from Asian T2DM patients in this study showed that the magnitude of OAD initiation and dose changes was slightly lower than the results of clinical trials


    Fang HSA, Gao Q, Tan WY, et al.




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