BMC Public Health: Less exposure to UVB light may increase the risk of colorectal cancer

Of colorectal cancer (CRC ) is the highest incidence of digestive tract, World Health Organization (WHO) International Agency for Research on Cancer (IARC) released 2020 global cancer burden latest data show that in 2020 the world's new colorectal cancer patients up 1.

Of colorectal cancer in colorectal cancer (CRC ) is the highest incidence of digestive tract, World Health Organization (WHO) International Agency for Research on Cancer (IARC) released 2020 global cancer burden latest data show that in 2020 the world's new colorectal There are 1.

Some of the risk factors associated with an increased risk of CRC include obesity, a sedentary life>

Recently , a study published in the open access journal BMC Public Health BMC Public Health study on the show , inadequate exposure to UVB light from the sun can increase the risk of colorectal cancer-related, especially in the elderly population

In this study , researchers at the University of California, San Diego investigated the possible association between global UVB light levels in 2017 and the incidence of colorectal cancer in different countries and age groups in 2018

In this study , researchers at the University of California, San Diego investigated the possible association between global UVB light levels in 2017 and the incidence of colorectal cancer in different countries and age groups in 2018

The authors found that among people living in the 186 countries/regions in the study, in all age groups from 0 to 75 years of age, lower UVB exposure was significantly associated with a higher incidence of colorectal cancer

Estimated crude incidence of CRC between 60 and 74 years of age estimated by UVB in 2018

Estimated crude incidence of CRC between 60 and 74 years of age estimated by UVB in 2018

The polynomial regression model of each age group between the adjusted UVB estimate and the crude incidence of CRC showed that the elderly group had a stronger negative correlation compared with the younger age group

The polynomial regression model of each age group between the adjusted UVB estimate and the crude incidence of CRC shows that compared with the younger age group, the elderly group has a stronger negative correlation.

The relationship between the estimated value of UVB using polynomial regression and the crude incidence of CRC The relationship between the estimated value of UVB using polynomial regression and the crude incidence of CRC

 In the multiple linear regression model, after controlling for covariates, UVB was negatively correlated with the crude incidence of colorectal cancer in all age groups over 45 years old ( p value <0.

 In the multiple linear regression model, after controlling for covariates, UVB was negatively correlated with the crude incidence of colorectal cancer in all age groups over 45 years old ( p p value <0.

After controlling for covariates, the relationship between UVB and the crude incidence of CRC over 75 years of age After controlling for the covariates, the relationship between UVB and the crude incidence of CRC over 75 years of age

The author believes that lower UVB exposure may reduce vitamin D levels

The author believes that lower UVB exposure may reduce vitamin D levels

In summary , in this country-specific analysis, the results of the study found that with age, the strength of the negative correlation between adjusted UVB estimates and the crude incidence of colorectal cancer showed an increasing trend

References: Vidya Lakshmi Purushothaman et al, Could age increase the strength of inverse association between ultraviolet B exposure and colorectal cancer?,  BMC Public Health  (2021).

 Vidya Lakshmi Purushothaman et al, Could age increase the strength of inverse association between ultraviolet B exposure and colorectal cancer?,  BMC Public Health BMC Public Health  (2021).

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