BMJ: After 22 years of follow-up, Chinese scholars found that eating garlic for a long time can reduce the mortality rate of stomach cancer.

In 2018, it is estimated that almost half of all stomach cancer deaths, the third-largest cause of cancer deaths worldwide, will occur in China.
Linyi County, shandong province in northeastern China, has one of the highest gastric cancer mortality rates in the world, with 55 deaths per 100,000 people and 19 deaths among women between 1980 and 1982.
epidemiological studies have strong evidence that Helicobacterrobacteria infections are associated with the development of pre-cancerous stomach lesions and stomach cancer, and suggest that a diet rich in vitamins and garlic can prevent stomach cancer in high-risk groups with insufficient vitamin intake.
In 1995, an intervention trial was conducted in Linyi County, Shandong Province, to assess the impact of three interventions on the progression of precancerogatives in the stomach: interventions included two weeks of helicobacter python therapy and more than seven years of treatment with vitamin and garlic supplements.
after nearly 15 years of follow-up (1995-2010), the trial reported a significant statistical decrease in the incidence of stomach cancer, but no statistically significant decrease in gastric cancer mortality associated with helicobacter pyrobacteria treatment.
Although the Shandong intervention test has shown that Helicobacterrobacteria therapy has potential role in preventing stomach cancer, further follow-up is needed to determine whether it will lead to a significant reduction in gastric cancer mortality over a longer period of time.
long term, it remains to be known whether vitamin and garlic supplements are associated with a significant statistical reduction in the incidence and mortality of stomach cancer.
, the researchers extended follow-up to more than 22 years to determine the incidence and mortality of stomach cancer.
the study recruited 3,365 residents in high-risk areas for stomach cancer, of whom 1,107 helicobacter pyridobacteria-negative residents were randomly assigned to vitamin supplementation, garlic supplementation or placebo groups.
2,258 Helicobacter pylus antibody-positive residents were randomly assigned to the Helicobacter pylosome treatment group (amoxilin and omeprazole combined treatment for 2 weeks), the vitamin supplementation group (ViC, E and selenium for 7.3 years), the garlic supplementation group (garlic extract and oil for 7.3 years) or the placebo group.
22 years (1995-2017) follow-up, 151 cases of stomach cancer and 94 deaths from stomach cancer were identified.
incidence of vitamin supplements decreased significantly, while garlic supplements did not.
all three interventions showed significant reductions in gastric cancer mortality: a fully adjusted risk ratio of 0.62 for Helicobacter pyridosis treatment, 0.48 for vitamin supplementation, and 0.66 for garlic supplementation.
no statistically significant correlation between interventions and other cancers or cardiovascular diseases.
Overall, follow-up 22 years found that helicobacteriosis treatment for two weeks, vitamin or garlic supplementation for seven years and gastric cancer death risk significantly reduced, Helicobacterrobacteria treatment and vitamin supplementation were also associated with a statistically significant reduction in the incidence of stomach cancer.
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