BMJ: After the first dose of AstraZeneca or Pfizer vaccine, the number of infections dropped by 65%

Preliminary results of a large surveillance study in the United Kingdom showed that after the first dose of Oxford-AstraZeneca or Pfizer-Biotech's vaccine, SARS-CoV-2 infections dropped by 65%.

infection

Studies have found that the benefits of the vaccine appear to be similar for people over 75 and under 75, as well as those with or without long-term health conditions.

Immunization In the case of the two vaccines, only a small percentage of people (about 5%) have a low response, and it is vital to monitor their response to the second dose of vaccine.

21 days after receiving a dose of AstraZeneca or Pfizer vaccine, SARS-CoV-2 infection decreased by 65% ​​(95% confidence interval 60%-70%), symptomatic infection decreased by 72% (69%-74%) And asymptomatic infections were reduced by 57% (64%-47%) ((all P<0.

The possibility of vaccinated people being re-infected with covid-19, and the possibility of continued transmission of vaccinated people is limited, even if the proportion is low.

The second study compared the changes in antibody concentrations in 45,965 people who received a single injection of AstraZeneca or Pfizer vaccine or two doses of Pfizer vaccine (usually 21-42 days apart).

The two doses of Pfizer drugs achieved high antibody responses in all age groups, especially increased seroconversion in the elderly, reaching a level similar to the single dose after the previous infection.

1 , Pritchard E, Matthews PC, Stoesser N, Eyre DW, Gethings O.

1 , Pritchard E, Matthews PC, Stoesser N, Eyre DW, Gethings O.
Impact of vaccination of SARS-CoV-ON 2 Cases in at The Community Community: A Population-based Study at The UK's Covid a using-19 Infection Survey.
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1 、Pritchard E, Matthews PC, Stoesser N, Eyre DW, Gethings O.
Impact of vaccination on SARS-CoV-2 cases in the community: a population-based study using the UK's Covid-19 Infection Survey.
Survey / Results / longer-Articles / Vaccine-Effectiveness .
href="" target="_blank" rel="noopener">2 , Wei J, N Stoesser, Matthews the PC, the Studley R & lt, of The Bell I.
Impact of SARS-CoV of ON-2 Vaccines Antibody Responses in The General Population in The United Kingdom.
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ndm.
ox.
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uk/covid-19/covid-19-infection-survey/results/longer-articles/vaccine-effectiveness .