echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Endocrine System > BMJ: Carbohydrate limiting the therapeutic effect of diet on type 2 diabetes

    BMJ: Carbohydrate limiting the therapeutic effect of diet on type 2 diabetes

    • Last Update: 2021-01-24
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com
    Dietary adjustment is an important aid to the treatment of diabetes, before the widespread clinical use of insulin, diabetics often need strict carbohydrate restriction diet.
    recently conducted a systematic review and meta-analysis to examine the effects of a low-carbohydrate diet on the treatment of type 2 diabetes.
    researchers collected studies from central, Medline, Embase, CINAHL, CAB and other databases as of August 2020.
    assessed the efficacy and safety of a low-carbohydrate diet that lasted at least 12 weeks (LCDs, carbohydrate intake below 130g/day or less than 26% of the energy provided by carbohydrates in a diet of no more than 2000 Kcal per day) and a very low-carbohydrate diet (VLCDs, carbohydrates provide less than 10% of energy). The main endpoints of the
    study were diabetes remission, defining HbA1c below 6.5% or peri-abdominal blood sugar below 7.0 mmol/L, weight loss, HbA1c levels, peritic blood sugar, and adverse events, with secondary endpoints including quality of life and laboratory bio-chemical data.
    a total of 23 studies, 1357 patient data were included in this meta-analysis, and 40.6% of the studies concluded that the risk of bias was low.
    study found that dietary control for six months had a higher rate of diabetes relief in the LCD population than in patients with a normal diet (HbA1c - 6.5% of patients: LCD vs normal diet group: 57% vs 31%, but in the absence of diabetes medication, the effect of THED decreased, while in the insulin-treated population, the effect was significant after LCD), but decreased when the LCD continued for 12 months.
    6 months, the LCD group had a significant effect on weight loss, triglyceride reduction and increased insulin sensitivity, but decreased at 12 months.
    there are reliable data showing that at 6 months, VLCD is less effective in weight loss than LCD, patient compliance may be the main factor explaining VLCD's poor effect, but for VLCD high compliance population, its weight loss effect is better than that of low compliance population.
    diet control had fewer effects on patients' quality of life, adverse events, and blood lipid levels.
    that a low-carbohydrate diet has a positive effect on disease control in people with type 2 diabetes, especially on the basis of appropriate drug intervention therapy.
    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.
    Related Articles

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent Echemi's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.