BMJ: Clinical differences among patients with new coronary pneumonia variant strains and vaccine efficacy studies

The global Covid-19 epidemic is still ongoing, and while vaccination and the advent of antiviral drugs continue to increase the stakes in defeating the epidemic, persistent genetic mutations in SARS-CoV-2 lead to changes in viral virulence or disease manifestations, making existing vaccines or treatments less effective.
Effectiveness decreases
.

At present, five new coronavirus variants have been identified by WHO as variant strains of concern, namely alpha (B.

The researchers examined the clinical severity of Covid-19 in patients infected

The vaccine was 85 percent effective against COVID-19-related hospitalizations due to the alpha variant and 94 percent effective against the delt variant

Significant improvement in clinical symptoms in vaccinated patients

Significant improvement in clinical symptoms in vaccinated patients Significant improvement in clinical symptoms in vaccinated patients

The study found that the mRNA vaccine is very effective in preventing hospital admissions caused by the new coronary pneumonia variant, but effective protection against the OmiCon variant can be achieved after a booster shot is required
.

The clinical manifestations of the vaccinated population after unfortunate infection were significantly lower than those of the unvaccinated population

The mRNA vaccine is very effective in preventing hospital admissions caused by the new coronary pneumonia variant, but requires a booster shot to achieve effective protection against the OmiCon variant
.
The clinical manifestations of the vaccinated population after unfortunate infection were significantly lower than those of the unvaccinated population
.
The mRNA vaccine is very effective in preventing hospital admissions caused by the new coronary pneumonia variant, but requires a booster shot to achieve effective protection against the OmiCon variant
.
The clinical manifestations of the vaccinated population after unfortunate infection were significantly lower than those of the unvaccinated population
.

Original Source:
Clinical severity of, and effectiveness of mRNA vaccines against, covid-19 from omicron, delta, and alpha SARS-CoV-2 variants in the United States: prospective observational study.
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