BMJ: Premenopausal non-malignant hysterectomy patients should be cautious about bilateral salpingo-ovarian resection

Bilateral salpingo-oophorectomy is traditionally an important method to prevent subsequent ovarian cancer , and is used for patients with non-malignant diseases that require hysterectomy
.

In recent years, as the potential harm of ovarian hormone deficiency is recognized, bilateral salpingo-oophorectomy should be avoided as much as possible

Guidelines for the Prevention of Ovarian Cancer Recently, researchers have investigated the impact of bilateral salpingo-oophorectomy compared with ovarian sparing in patients undergoing hysterectomy for non-malignant diseases on the risk of subsequent death, and the impact of surgical age on the prognosis .

This study is a population-based cohort study, collecting data on patients with hysterectomy from January 1, 1996 to December 31, 2015, and from 2017 to December 31, 2017 in Ontario, Canada, with a total of 200549 patients (age 30-70 years old) underwent non-malignant hysterectomy.

According to the age of operation, it is divided into premenopausal (<45 years old), menopausal transition period (45-49 years old), early menopause (50-54 years old) and postmenopausal (≥55 years) Years), with a median follow-up time of 12 years

Among female patients under the age of 45, 45-49, 50-54, and ≥55 years of age, 19%, 41%, 69%, and 81% had bilateral salpingo-oophorectomy, respectively
.

The study found that compared with ovarian preservation, women under 45 years old (hazard ratio 1.
31) and women aged 45-49 years (1.

The study found that compared with ovarian preservation, women under 45 years old (hazard ratio 1.

Differences in the risk of death after bilateral salpingo-oophorectomy in different age groups

Differences in the risk of death after bilateral salpingo-oophorectomy in different age groups Differences in the risk of death after bilateral salpingo-oophorectomy

The study found that patients with non-malignant diseases under the age of 50 who underwent bilateral salpingo-ovarian hysterectomy have an increased risk of postoperative all-cause death, but those over the age of 50 are not affected
.

Patients with non-malignant diseases under 50 years of age who undergo bilateral salpingo-ovarian hysterectomy have an increased risk of all-cause death after surgery, but people over 50 years of age are not affected
.

Patients with non-malignant diseases under 50 years of age who undergo bilateral salpingo-ovarian hysterectomy have an increased risk of all-cause death after surgery, but people over 50 years of age are not affected

Original source:

Maria C Cusimano et al.

Association of bilateral salpingo-oophorectomy with all cause and cause specific mortality: population based cohort study.
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