Body fat distribution may be related to high-risk prostate cancer

Original source: Wikipedia < br / > previous studies have shown that obesity is directly related to high-risk prostate cancer and poor prognosis of patients after diagnosisIn addition, studies have also shown that the special distribution of body fat may be an important factor in the risk of prostate cancerIn order to provide high-quality evidence, the researchers conducted a 13-year follow-up study on 1832 Icelandic male patients, analyzed the body fat distribution of participants by means of the gold standard of computed tomography, and evaluated the risk of patients diagnosed with prostate cancer and death due to prostate cancer< br / > during the study period, 172 men suffered from prostate cancer, 31 of whom diedThe researchers found that the accumulation of fat in special areas of the body was related to the occurrence of malignant and fatal prostate cancer, including visceral areas, subcutaneous thighs, etc.; in addition, higher body mass index and waist circumference were also related to the risk of malignant and fatal prostate cancerResearcher Dickerman points out that, more interesting, when we compared the participants with high BMI and low BMI, the association between visceral fat accumulation and the incidence rate of malignant and fatal prostate cancer was particularly evident among participants with low body mass index, which were limited in subgroup analysisHowever, it has certain guiding significance for future research< br / > later researchers need to conduct more in-depth research to investigate the key role of fat distribution in the occurrence and progression of prostate cancer, At the same time, they also want to clarify how changes in fat storage affect patients' health over time; identify fat distribution patterns related to the occurrence of high-risk prostate cancer or hopefully help researchers to clarify the molecular mechanism of obesity associated with malignant diseases, and also hope to help develop new therapies targeted at male prostate cancer< br / > in a subsequent editorial, the researchers said lifestyle interventions such as diet and exercise could also help reduce an individual's risk of prostate cancer< br / > original source: < br / > Barbra aDickerman, Johanna Etorfadottir, unnur avaldimarsdotir, et al.Bodyfat distribution on CT imaging and prostate cancer risk and mortality in the AGES-ReykjavikStudy.Cancer (2019)doi:10.1002/cncr.32167Celina H Shirazipour,Stephen J Freedland.Obesity , visceral and prostate cancer: What is the role of lifestyle interventions?Cancer(2019) doi:10.1002/cncr.32165