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    Home > Active Ingredient News > Antitumor Therapy > Br J Cancer: Even if the weight is normal, body fat indicators are also related to the risk of cancer

    Br J Cancer: Even if the weight is normal, body fat indicators are also related to the risk of cancer

    • Last Update: 2021-03-30
    • Source: Internet
    • Author: User
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    Obesity is considered to be one of the risk factors for at least 13 different types of cancer.
    In order to determine the level of body fat, most epidemiological studies use body mass index (BMI, calculated as weight (kg)/height (m2)).
    However, the relationship between the body fat composition of people with normal weight (BMI: 18.
    5–24.
    9 kg/m2) and the risk of cancer is currently unclear.

    Obesity is considered to be one of the risk factors for at least 13 different types of cancer.
    Obesity is considered to be one of the risk factors for at least 13 different types of cancer.
    The relationship between the body fat composition of people with normal weight (BMI: 18.
    5–24.
    9 kg/m2) and the risk of cancer is currently unclear.
    The relationship between the body fat composition of people with normal weight (BMI: 18.
    5–24.
    9 kg/m2) and the risk of cancer is currently unclear.

    In this study, the researchers analyzed 149,928 normal-weight individuals (40-70 years old) who were included in the UK Biobank cohort between 2006 and 2010 to study obesity and breast cancer (postmenopausal), The correlation of the risk of endometrial cancer, ovarian cancer and colorectal cancer .

    Breast cancer, ovarian cancer, colorectal cancer

    The results showed that all body fat indexes were positively correlated with the risk of invasive breast cancer after menopause.
    The trunk fat mass index and waist circumference (WC) are positively correlated with the risk of endometrial cancer.
    In men, trunk:thigh fat mass ratio and trunk:thigh fat mass ratio are positively correlated with the risk of colon cancer .
    The body fat index of women has nothing to do with the risk of ovarian cancer or colorectal cancer.

    Colon cancer

    Relevant characteristics of participants in the UK Biobank

    In summary, the results of the study show that the data of related fat components in the normal weight population based on BMI shows a correlation with the increased risk of obesity-related cancers.

    The related fat composition data in normal weight population based on BMI shows a correlation with an increased risk of obesity-related cancer.
    The related fat composition data in normal weight population based on BMI shows a correlation with an increased risk of obesity-related cancer.


    Original source:


    Arthur, RS, Dannenberg, AJ, Kim, M.


    et al.
    org/10.


    org/10.


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