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    Home > Active Ingredient News > Antitumor Therapy > Br J Cancer: Sodium ion concentration in breast cancer predicts tumor malignancy and treatment response

    Br J Cancer: Sodium ion concentration in breast cancer predicts tumor malignancy and treatment response

    • Last Update: 2022-05-20
    • Source: Internet
    • Author: User
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    Metastatic breast cancer is one of the leading causes of cancer-related deaths in women worldwide, and the triple-negative breast cancer subtype corresponds to a poorer prognosis for patients


    Metastatic breast cancer is one of the leading causes of cancer-related deaths in women worldwide, and the triple-negative breast cancer subtype corresponds to a poorer prognosis for patients


    Previous studies have shown that, unlike traditional proton-based imaging techniques, non-invasive 23 Na MRI based on intratumoral sodium ion concentration (Na + ) may be a biomarker for breast cancer .


    Unlike traditional proton-based imaging techniques, non-invasive 23 Na MRI based on intratumoral sodium ion concentration (Na + ) may be a biomarker for breast cancer .




    23 Na MRI results showed that the sodium ion concentration (Na + ) in the tumor was significantly higher than that in the non-tumor area




    The + 23 Na MRI imaging technique can enhance the diagnostic power of DWI with higher sensitivity, which may serve as a potential non-invasive biomarker of disease malignancy and treatment response



    James, AD, Leslie, TK, Kaggie, JD et al.


    https://doi.
    org/10.
    1038/s41416-022-01802-w.


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