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In the study, researchers in subjects with non-alcoholic fatty liver disease explored a mixture of natural ingredients, namely DHA, phosphatidylcholine, hydrophilia, choline, curcumin, and d-alpha-procoptol.
the main endpoint is serum liver enzyme level, other liver function parameters, metabolic syndrome and inflammation as the secondary endpoint.
, as non-alcoholic fatty liver is associated with hemostatic changes, may lead to an increased cardiovascular risk of the disease, a comprehensive investigation was conducted into the balance of clotting-fiuprotein dissolution.
the study involved two parallel groups of double-blind, randomized, multi-center control trials.
participants (18-80 years of age, men and women) who were included in the NAFLD received active or controlled treatment for 3 months.
all tests were conducted on 113 subjects before and at the end of complementary treatment. After
treatment, the level of hepatoenzyme Tianmen doninemide metalyse (AST), alanine amino metase and gamma-glutamine transpeptidease decreased from 23-2% to 3-7%, and only AST levels reached statistical significance.
but there was no difference between the control group and the activity group. there was no change in
metabolic and inflammatory variables, except for a slight increase in cholesterol and glucose levels (less than 10%) after active therapy.
clotting-fiuprotein dissolution parameters are not affected by the two treatments.
in general, the chronic dietary compound mixture was well tolerated and clearly safe among NAFLD subjects.
the trial has failed to demonstrate any efficacy against related physiological pathological markers, but its programmes and results may be useful for the design of future natural compounds.
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