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    Home > Biochemistry News > Biotechnology News > Bristol-Myers Squibb S1P receptor modulator gains new indications for the treatment of ulcerative colitis

    Bristol-Myers Squibb S1P receptor modulator gains new indications for the treatment of ulcerative colitis

    • Last Update: 2021-06-05
    • Source: Internet
    • Author: User
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    Bristol-Myers Squibb (BMS) today announced that the US FDA has approved Zeposia (ozanimod) 0.


    This approval is based on the results of a pivotal Phase 3 clinical trial called True North.


    Ulcerative colitis is a chronic inflammatory bowel disease (IBD), which is characterized by a long-term abnormal immune response that leads to persistent inflammation and ulcers in the mucous membrane of the colon or rectum.


    Zeposia (ozanimod) is an oral S1P receptor modulator that binds to S1P receptors 1 and 5 with high affinity.


    Note: The original text has been deleted

    Reference materials:

    [1] US Food and Drug Administration Approves Bristol Myers Squibb's Zeposia® (ozanimod), an Oral Treatment for Adults with Moderately to Severely Active Ulcerative Colitis.


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