-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
- Cosmetic Ingredient
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
Deficiencies of B vitamins such as folic acid and vitamin B12 are very common in the elderly
.
It is reported that one in eight elderly people in Ireland has low B12 levels.
Recently, a study published in the famous "British Journal of Nutrition" showed that low vitamin B12 levels are related to depressive symptoms, but folic acid has nothing to do with depression
.
Eamon Laird et al, Low vitamin B12 but not folate is associated with incident depressive symptoms in community-dwelling older adults: a 4 year longitudinal study, British Journal of Nutrition (2021).
DOI: 10.
1017/S0007114521004748
DOI: 10.
1017/S0007114521004748
The study used data from a longitudinal study on aging in Ireland and analyzed 3849 participants over the age of 50.
The researchers observed that those with insufficient B12 intake were 51% more likely to develop depressive symptoms within 4 years
.
Low levels of B12 are associated with a significant increase in the risk of depressive symptoms within four years, but no such association with folic acid has been observed
Even controlling for relevant adjustment factors, such as physical activity, the burden of chronic disease, vitamin D , heart blood vessels use disorders and antidepressant, found that this is still convincing
.
Researchers have found that as age increases, the risk of depression decreases
Vitamin D blood vessels
The study investigated the relationship between plasma folic acid and B12 levels at baseline (wave 1) and depression at 2 and 4 years (waves 2 and 3)
.
Participants with depression at baseline were excluded
Compared with non-depressive patients, the plasma concentrations of B12 and folic acid are lower in patients with depression (folate: 21.
4 vs.
25.
1 nmol/L; P=0.
0003), (B12: 315.
7 vs.
335.
9 pmol/L; P= 0.
0148)
.
The regression model showed that participants with B12 deficiency at baseline were significantly more likely to develop depression after four years (OR: 1.
Dr.
Eamon Laird, the lead author of the study, said
.
"The elderly living in Ireland have a high incidence of depression, and there is evidence that one in eight elderly people is highly B12 deficient
"Our research results should provide policymakers with further assurance that food fortification policies can provide a potential means to help prevent depressive symptoms in the elderly, and through foods such as breakfast cereals rich in B12 vitamins and folic acid.
Good for overall health
.
"prevention
In view of the increase in loneliness and depression among the elderly after the COVID-19 restriction began, this study emphasizes the importance of increasing B12 intake or supplementation to help reduce potential risk factors for depression in the elderly
COVID-19
Reference materials:
Eamon Laird et al, Low vitamin B12 but not folate is associated with incident depressive symptoms in community-dwelling older adults: a 4 year longitudinal study, British Journal of Nutrition (2021).
Eamon Laird et al, Low vitamin B12 but not folate is associated with incident depressive symptoms in community-dwelling older adults: a 4 year longitudinal study, British Journal of Nutrition (2021) DOI:.
10.
1017 / S0007114521004748 in this message
