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    Home > Active Ingredient News > Drugs Articles > Broccoli may improve blood glucose in diabetic patients

    Broccoli may improve blood glucose in diabetic patients

    • Last Update: 2017-07-11
    • Source: Internet
    • Author: User
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    [China Pharmaceutical network industry trends] now, type 2 diabetes has become more and more common, but not all patients can be successfully treated by existing drugs Scientists are also looking for new ways to help diabetics control their blood sugar Recently, a group of researchers from Sweden, the United States and Switzerland found that sulforaphane, a common compound in cruciferous vegetables, can reduce the glucose production of rat liver cells and improve the fasting blood glucose of diabetic patients The study was recently published in Science Translational Medicine (picture source: Baidu picture) at present, diabetes has become one of the serious public health problems in the world In 2015, data released by the International Diabetes Federation showed that the death rate of diabetes was higher than that of AIDS, tuberculosis and malaria combined, and about one diabetic died every six seconds The number of adult diabetics in the world has reached 415 million Common treatments for diabetes include diet control and medication such as metformin But diabetes drugs can also cause other problems, such as liver damage, so researchers are trying to find alternatives In this new study, the researchers analyzed the gene expression patterns associated with type 2 diabetes and compared them with the gene markers of thousands of candidate drugs to find compounds related to gene expression specificity in hepatocytes The researchers finally found that sulforaphane, a natural compound commonly found in cruciferous vegetables such as broccoli, has a strong effect on gene expression related to diabetes The researchers then cultured hepatocytes from type 2 diabetic rats and treated them with sulforaphane The results showed that sulforaphane could inhibit the production of glucose in cultured cells and improve the glucose tolerance of rodents on a high-fat or high sugar diet In view of the optimistic results of cell and animal experiments, the following researchers conducted clinical experiments They tested sulforaphane in 97 obese type 2 diabetic patients over a 12 week period It was found that the glucose level of patients treated with sulforaphane decreased significantly on an empty stomach However, the results of this study are still in the early stage, and more tests are needed to prove the efficacy of sulforaphane, to prove that this compound or just by eating vegetables such as broccoli may replace the drugs of type 2 diabetes Extended reading: the secret of the anti-cancer effect of broccoli - regulating lncrna seems to be often found in various research related to diet and health care, which is indispensable for delaying aging, strengthening the immune system and inhibiting cancer Previous studies have shown that sulforaphane, a compound found in cruciferous vegetables such as broccoli, can help prevent or slow cancer progression Recently, a study published by Oregon State University in the Journal of nuclear biology revealed the mechanism behind this It was found that sulforaphane may play a role in inhibiting cancer through its effect on long noncoding RNA.
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