Brown fat and gut hormones send a signal to the brain that it's "full."

We usually think that obesity is more associated with "fat".
, however, a previous article in the latest issue of Cell offers a different conclusion - there is one type of fat that may be associated with weight loss! Scientists have found that this type of fat interacts with gut hormones, which in turn sends a signal to the brain that it is "full."
our body contains two types of fats that are very different in shape and function: white fat and brown fat (BAT).
, white fat accumulates under the skin and is responsible for storing excess calories, causing obesity, while brown fat burns fat and turns it into heat, which is key to keeping a mammal's body temperature. On November 15,
, the journal Cell published an article entitled "Secretin-Activated Brown Fat Media SPreic Sitgeness to Satiation", revealing another new feature of BAT: regulating satiety.
martin Klingenspor team at the Technical University of Munich in Germany found that there is a complex regulatory system between the gut, brain and brown fat that controls energy balance.
"Brown fat is more than just a 'heat-producing organ'.
," stressed Martin Klingenspor.
in addition to brown fat, another "main protagonist" of the study is the intestinal hormone, Mytryn.
this hormone was discovered in 1902 to stimulate the pancreas, which secretes bicarbonate of salt, which in turn helps the small intestine neutralise acid and digests large amounts of nutrients.
more than a hundred years later this year, scientists have found that the hormone has another understated effect, which activates brown fat, which causes the latter to produce satiety signals.
researchers further validated the findings by modeling hungry mice and found that artificial injections of pancreatic liquefied acid inhibited appetite in mice and increased the amount of calories produced by brown fat.
However, when mice carry inactive brown fat (mutation), even injections of pantryin do not produce an appetite suppressor.
in addition to studying the effects of pancreatitis on brown fat in mice, the team also measured pancreatic levels among 17 volunteers.
specifically, the researchers took blood samples from the subjects on their fasting overnight stomachs and 30-40 minutes after meals, from which they tested brown fat oxygen consumption and fatty acid absorption.
results showed that the higher the level of panelin in the blood, the more active the metabolism of brown fat. "Any stimulation that induces brown fat to grow hot can lead to a feeling of satiety," says Martin Klingenspor,
.
the secretion of pantry is sensitive to nutrients, selecting certain foods can help promote satiety, thereby reducing the desire for food and intake.
" he believes brown fat plays an important role in controlling hunger and is expected to become a new target for the treatment of obesity, for example, by targeting brown fat with pancreatic fluid, with the opportunity to change the nutritional or drug intervention patterns of obesity and other metabolic diseases.
Source: Biological Exploration.