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Editor’s note iNature is China’s largest academic official account.
It is jointly created by the doctoral team of Tsinghua University, Harvard University, Chinese Academy of Sciences and other units.
The iNature Talent Official Account is now launched, focusing on talent recruitment, academic progress, scientific research information, interested parties can Long press or scan the QR code below to follow us.
iNature recently, the American Cancer Society Ma Jiemin (transliteration, former Hebei Medical University graduate) team published an online research paper entitled "The American Cancer Society 2035 challenge goal on cancer mortality reduction" in CA (IF=292).
The paper pointed out that: The 2015 American Cancer Society (ACS) challenge target summary assessment showed that between 1990 and 2015, the overall mortality rate of all cancers dropped by 26%.
Recent studies have shown that through relevant interventions, cancer mortality in the United States can still be significantly reduced.
According to the corresponding model prediction, the American Cancer Society’s 2035 challenge target is set to be 40% lower than the 2015 level.
Achieving this goal may reduce the number of cancer deaths by approximately 1.
3 million compared to 2020-2035, and the number of cancer deaths in 2035 alone will be reduced by 122,500.
In the past 60 years, cancer research has produced important knowledge about its causes, screening, diagnosis, and treatment.
Unfortunately, this knowledge is not implemented consistently and fairly across the entire population.
In fact, if all sectors of society enjoy good preventive and therapeutic care, cancer mortality can be greatly reduced.
The greatest reward for cancer deaths is through continued tobacco control efforts and then efforts to control weight.
This requires changes in demographic and cultural behavior to a degree very similar to the changes in smoking since the mid-1960s.
Such a change will reduce the incidence and mortality of cancer for the 2035 target, and will also reduce the incidence and mortality of several other chronic diseases, including cardiovascular disease and diabetes.
In order to achieve the challenge of reducing cancer mortality by 2035, high-quality medical services (including prevention and treatment) must be widely and equitably obtained and utilized.
Finally, the research has reference significance for other countries to formulate cancer challenge targets, and at the same time has an important role in promoting cancer prevention.
Over the years, public health organizations have carried out future activities and issued cancer challenge targets in an attempt to motivate and guide cancer control activities.
In 1981, Doll and Peto published a classic article on the causes of cancer, emphasizing the impact of tobacco on cancer mortality.
They estimated that these mortality rates accounted for about 30% of cancer deaths in the United States.
This led to the National Cancer Institute (NCI) in 1986 calling for efforts to halve cancer mortality between 1985 and 2000.
In 1996, the American Cancer Society (ACS) Board of Directors issued a challenge target.
Overall, between 1990 and 2015, all cancer deaths in the United States have dropped by 26%: in 25 years, lung cancer deaths (45% of men are , Women accounted for 8%), colorectal cancer (47% for men and 44% for women), breast cancer (39%) and prostate cancer (53%) in women all achieved a decline; all other cancers fell by 13 in men %, a decrease of 17% among women.
These declines are thought to reflect a reduction in tobacco use and improvements in early detection and treatment.
However, in the past few decades, scientists and researchers from other institutions have reported that there are huge differences in the progress of anti-cancer among people defined by race/ethnicity, area of residence, and socioeconomic status (SES).
These findings indicate that not all Americans can benefit from advances in cancer prevention, early detection, and treatment.
In view of the above findings, the American Cancer Society’s board of directors commissioned researchers from the American Cancer Society’s internal research department to predict the cancer mortality rate in the United States by 2035 and determine the challenge target.
The question to be solved is: if the current trend continues, what will be the cancer mortality rate in 2035? By accelerating progress in reducing cancer mortality (a challenge goal), what will happen to cancer mortality in 2035? What is the way to achieve the 2035 challenge target? The statistical model is used to estimate the average annual decrease in the overall cancer mortality rate among the general population and the university-educated population in the United States; then, the average annual percentage decrease in the overall cancer mortality rate of college graduates is applied to the mortality rate in the general population to predict by 2020 The future incidence rate in the United States in 2015.
If the overall cancer mortality rate declines nationwide from 2020 to 2035 compared with college graduates, the US mortality rate in 2035 will be 38.
3% lower than the 2015 level and 54.
4% lower than the 1990 level.
On the basis of these results, the American Cancer Society’s 2035 challenge target is set to be 40% lower than the 2015 level.
Achieving this goal may reduce the number of cancer deaths by approximately 1.
3 million compared to 2020-2035, and the number of cancer deaths in 2035 alone will be reduced by 122,500.
The results also show that reducing the prevalence of risk factors and achieving optimal compliance with evidence-based screening guidelines by 2025 can lead to a 33.
5% reduction in overall cancer mortality by 2035, reaching the challenged target of 85%.
In the past 60 years, cancer research has produced important knowledge about its causes, screening, diagnosis, and treatment.
Unfortunately, this knowledge is not implemented consistently and fairly across the entire population.
In fact, if all sectors of society enjoy good preventive and therapeutic care, cancer mortality can be greatly reduced.
The future progress of the "Cancer War" depends on the extent to which policymakers and the public can unite to establish a system to provide adequate medical care for all.
The greatest reward for cancer deaths is through continued tobacco control efforts and then efforts to control weight.
This requires changes in demographic and cultural behavior to a degree very similar to the changes in smoking since the mid-1960s.
Such a change will reduce the incidence and mortality of cancer for the 2035 target, and will also reduce the incidence and mortality of several other chronic diseases, including cardiovascular disease and diabetes.
Previous studies have shown that the treatment effect received by a considerable number of people is not satisfactory.
In order to achieve the challenge of reducing cancer mortality by 2035, high-quality medical services (including prevention and treatment) must be widely and equitably obtained and utilized.
Reference message: https://onlinelibrary.
wiley.
com/doi/full/10.
3322/caac.
21564
It is jointly created by the doctoral team of Tsinghua University, Harvard University, Chinese Academy of Sciences and other units.
The iNature Talent Official Account is now launched, focusing on talent recruitment, academic progress, scientific research information, interested parties can Long press or scan the QR code below to follow us.
iNature recently, the American Cancer Society Ma Jiemin (transliteration, former Hebei Medical University graduate) team published an online research paper entitled "The American Cancer Society 2035 challenge goal on cancer mortality reduction" in CA (IF=292).
The paper pointed out that: The 2015 American Cancer Society (ACS) challenge target summary assessment showed that between 1990 and 2015, the overall mortality rate of all cancers dropped by 26%.
Recent studies have shown that through relevant interventions, cancer mortality in the United States can still be significantly reduced.
According to the corresponding model prediction, the American Cancer Society’s 2035 challenge target is set to be 40% lower than the 2015 level.
Achieving this goal may reduce the number of cancer deaths by approximately 1.
3 million compared to 2020-2035, and the number of cancer deaths in 2035 alone will be reduced by 122,500.
In the past 60 years, cancer research has produced important knowledge about its causes, screening, diagnosis, and treatment.
Unfortunately, this knowledge is not implemented consistently and fairly across the entire population.
In fact, if all sectors of society enjoy good preventive and therapeutic care, cancer mortality can be greatly reduced.
The greatest reward for cancer deaths is through continued tobacco control efforts and then efforts to control weight.
This requires changes in demographic and cultural behavior to a degree very similar to the changes in smoking since the mid-1960s.
Such a change will reduce the incidence and mortality of cancer for the 2035 target, and will also reduce the incidence and mortality of several other chronic diseases, including cardiovascular disease and diabetes.
In order to achieve the challenge of reducing cancer mortality by 2035, high-quality medical services (including prevention and treatment) must be widely and equitably obtained and utilized.
Finally, the research has reference significance for other countries to formulate cancer challenge targets, and at the same time has an important role in promoting cancer prevention.
Over the years, public health organizations have carried out future activities and issued cancer challenge targets in an attempt to motivate and guide cancer control activities.
In 1981, Doll and Peto published a classic article on the causes of cancer, emphasizing the impact of tobacco on cancer mortality.
They estimated that these mortality rates accounted for about 30% of cancer deaths in the United States.
This led to the National Cancer Institute (NCI) in 1986 calling for efforts to halve cancer mortality between 1985 and 2000.
In 1996, the American Cancer Society (ACS) Board of Directors issued a challenge target.
Overall, between 1990 and 2015, all cancer deaths in the United States have dropped by 26%: in 25 years, lung cancer deaths (45% of men are , Women accounted for 8%), colorectal cancer (47% for men and 44% for women), breast cancer (39%) and prostate cancer (53%) in women all achieved a decline; all other cancers fell by 13 in men %, a decrease of 17% among women.
These declines are thought to reflect a reduction in tobacco use and improvements in early detection and treatment.
However, in the past few decades, scientists and researchers from other institutions have reported that there are huge differences in the progress of anti-cancer among people defined by race/ethnicity, area of residence, and socioeconomic status (SES).
These findings indicate that not all Americans can benefit from advances in cancer prevention, early detection, and treatment.
In view of the above findings, the American Cancer Society’s board of directors commissioned researchers from the American Cancer Society’s internal research department to predict the cancer mortality rate in the United States by 2035 and determine the challenge target.
The question to be solved is: if the current trend continues, what will be the cancer mortality rate in 2035? By accelerating progress in reducing cancer mortality (a challenge goal), what will happen to cancer mortality in 2035? What is the way to achieve the 2035 challenge target? The statistical model is used to estimate the average annual decrease in the overall cancer mortality rate among the general population and the university-educated population in the United States; then, the average annual percentage decrease in the overall cancer mortality rate of college graduates is applied to the mortality rate in the general population to predict by 2020 The future incidence rate in the United States in 2015.
If the overall cancer mortality rate declines nationwide from 2020 to 2035 compared with college graduates, the US mortality rate in 2035 will be 38.
3% lower than the 2015 level and 54.
4% lower than the 1990 level.
On the basis of these results, the American Cancer Society’s 2035 challenge target is set to be 40% lower than the 2015 level.
Achieving this goal may reduce the number of cancer deaths by approximately 1.
3 million compared to 2020-2035, and the number of cancer deaths in 2035 alone will be reduced by 122,500.
The results also show that reducing the prevalence of risk factors and achieving optimal compliance with evidence-based screening guidelines by 2025 can lead to a 33.
5% reduction in overall cancer mortality by 2035, reaching the challenged target of 85%.
In the past 60 years, cancer research has produced important knowledge about its causes, screening, diagnosis, and treatment.
Unfortunately, this knowledge is not implemented consistently and fairly across the entire population.
In fact, if all sectors of society enjoy good preventive and therapeutic care, cancer mortality can be greatly reduced.
The future progress of the "Cancer War" depends on the extent to which policymakers and the public can unite to establish a system to provide adequate medical care for all.
The greatest reward for cancer deaths is through continued tobacco control efforts and then efforts to control weight.
This requires changes in demographic and cultural behavior to a degree very similar to the changes in smoking since the mid-1960s.
Such a change will reduce the incidence and mortality of cancer for the 2035 target, and will also reduce the incidence and mortality of several other chronic diseases, including cardiovascular disease and diabetes.
Previous studies have shown that the treatment effect received by a considerable number of people is not satisfactory.
In order to achieve the challenge of reducing cancer mortality by 2035, high-quality medical services (including prevention and treatment) must be widely and equitably obtained and utilized.
Reference message: https://onlinelibrary.
wiley.
com/doi/full/10.
3322/caac.
21564
