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    Home > Active Ingredient News > Immunology News > Can humans really achieve COVID-19 zero infection? This may take quite some time!

    Can humans really achieve COVID-19 zero infection? This may take quite some time!

    • Last Update: 2020-10-27
    • Source: Internet
    • Author: User
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    October 26, 2020 // -- Most scientists now agree that in order to limit the spread of SARS-CoV-2, we need to adopt strict controls, including effective contact tracing, detection and isolation, as well as social distance, wearing masks, and so on, and countries such as South Korea, China and New Zealand have successfully used this method to successfully curb the spread and spread of the virus.
    Some have even called for a zero-COVID-19 patient approach to try to eradicate the virus rather than curb its spread, which New Zealand seems to have succeeded in, but after 100 days without new cases, new infections have re-emerged and come from international travel and other unknown sources.
    the use of these controls to level out the districts and counties where the number of people infected is possible, it may not be feasible to achieve COVID-19 zero infection.
    Photo Source: GroundUp may be possible for some island nations, in New Zealand, for example, to prevent the virus from re-entering, which of course may require long and strict travel restrictions and very strict nucleic acid testing of passengers before and after travel.
    Given that interest in extending border closures is not very high and that community-based controls are not sufficient to eliminate the virus, achieving zero infection at the moment seems unlikely, but it may be possible in the future if we use different approaches.
    The most effective way to suppress COVID-19 infection is to use the natural defense mechanism of the human body, that is, the immune system, recovering from the virus infection process is usually related to the body's immunity, then infected with SARS-CoV-2 can protect the body from re-infection by the virus, researchers do not know, but few cases of re-infection.
    Most infected people produce antibodies against SARS-CoV-2, and some asymptomatic infections may not produce antibodies, but the infection still activates the body's immune system T cells, providing an alternative defense mechanism, so it seems that the infection will produce immunity in most people, at least in the short term.
    Understand this, some scientists have suggested that the virus should be allowed to spread in the population so that the group's immunity can develop, while protecting the elderly and vulnerable people, so that enough people can develop immunity, thereby blocking the spread and spread of the disease, for high levels like measles The threshold for transmission of the virus is as high as 90-95%, while some believe it may be as low as 50% for SARS-CoV-2, and the consensus among experts is about 60%-70%.
    However, the proportion of people currently infected with SARS-CoV-2 and recovering has not reached this level, and antibody studies show that about 3 per cent of people in Dublin have been infected with the virus, perhaps a higher proportion in New York City, or 23 per cent;
    In these places, the second wave of effects may be lower, because many people have a pound of infection, but if the threshold for group immunization is not reached, the entire population still seems unpulable, and the consequences of trying to reach that threshold through natural infections may be more high-risk deaths, including the elderly, obese and people with underlying diseases;
    , for most people, the risks associated with pursuing group immunity make it an unacceptable strategy to suppress the virus, let alone eliminate it.
    However, in theory, mass immunization through vaccination may lead us to an elusive zero-infection situation, and in many developed countries vaccines have reduced the incidence of diseases such as diphtheria, tetracytics and measles to near zero.
    There are currently more than 200 SARS-CoV-2 vaccines under development, but if there is a vaccine that can completely eliminate COVID-19, the threshold may be a little higher, and any vaccine needs to be very effective in preventing disease and blocking its spread in the population.
    Photo Source: thetraveldoctor.com.au However, the fastest-developed vaccine has turned its attention to a lower goal: at least 50 percent effectiveness, which is the threshold it needs to get FDA approval, scientists' first attempt to develop an effective vaccine may be an optimistic idea, and the vaccine needs to be effective for all ages, and safety is key, because any problems that arise in any age group will make them confident and willing to vaccinate.
    will also need to produce enough vaccines to vaccinate more than 7 billion people around the world, which will take time; AstraZeneta, for example, which is developing a new crown vaccine, has now reached an agreement to produce 2 billion doses by the end of 2021.
    CoVID-19's human impact may not have been immediate, with the last case of natural smallmatocy occurring in 1977, 10 years after the WHO launched its smallchim eradication programme and nearly 200 years after the first small-flower vaccine was developed, and nearly 30 years from polio eradication initiatives to polio eradication in areas other than Pakistan and Afghanistan.
    Therefore, while an effective vaccine provides humans with the best chance of contracting COVID-19 zero infection, we should remain realistic about what may happen, and eliminating the virus in most parts of the world, while not unthinkable, may take a considerable amount of time.
    () Reference: 1 Argument for New Zealand-style Zero-COVID strategy strong, experts say?2?the dynamics of humoral immune responses after SARS-CoV-2 infect and the potential for reinfection (3) Coronavirus (COVID-19) deaths worldwide per million people of October 23, 2020, By country(4) Is reaching. Zero COVID-19 possible? by Kingston Mills, The Conversation <!--/ewebeditor:page->.
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