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    Home > Biochemistry News > Biotechnology News > Can red wine lower blood pressure? Is resveratrol really magical?

    Can red wine lower blood pressure? Is resveratrol really magical?

    • Last Update: 2020-06-03
    • Source: Internet
    • Author: User
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    The French diet often have high fat and high cholesterol food, but the incidence of cardiovascular disease is relatively low, this is the academic world's famous "French paradox." The researchers put forward a variety of hypotheses that they wished to explain the French paradoxThe French drink red wine, and resveratrol in red wine was once known as the mystery behind the French paradoxresveratrol, a non-flavonoid polyphenol compound, was first found in the lily squalorgen plant Ofacur squaloria, and was later found in a variety of plants, especially fruits, and the presence of resveratrol, best known as grapesresveratrol was initially considered only as a plant antitoxin (a substance produced by plant resistance to disease), but subsequent studies have shown that resveratrol, under laboratory conditions, has shown anti-inflammatory, antioxidant and extended effects on a variety of experimental microorganisms and animals, such as yeast, worms, mice, etc.;recently, Circulation, a unit of the American Heart Association, published a new study on resveratrol's blood pressureDrOleksandra Prysyazhna, of King's College London, and other researchers have proposed a new interpretation of the mechanism of resveratrol blood pressure reduction through a series of studies on vascular smooth muscle cells and mice: resveratrol is used to mediate the effect sesamein blood vessels, especially in the context of oxidation stress, by inducing the oxidation modification of pynothnosin-dependent protein kinase (PKGI alpha), which is particularly evident in the context of oxidative stresspicture source: Circulation's websitethis new research paper appears to be another strong evidence of the "magical effect" of resveratrol, but academic experts have different views on itProfessor Roger Cordor, of Queen Mary University of London, argues that the mechanism of resveratrol blood pressure reduction mentioned in the paper is not so much the pharmacological effect of resveratrol as the result of laboratory conditions far above normal medicinal concentrationsThis "off-target effect" on protein oxidation modification is likely to do more harm than good to healthProfessor Roger Cordor,, added, "This study does not propose a dose threshold for resveratrol's blood pressure reduction effectThe mice in the study received an extremely high dose of 320 mg/kg, which is equivalent to 15-20 grams of resveratrol, which is equivalent to drinking about 3,000 liters of red wine (equivalent to 4,000 bottles of red wine at 750 ml) if they were consumed with such a high dose of resveratrol through red wine." Dr Bob Patton, of the University of Surrey, made a similar observation: "The researchers in this paper demonstrated that resveratrol has a significant effect on blood pressure lowering in mice using very high doses under laboratory conditionsBut the authors also point out that these effects have not been proven in humans"urban legend" about lowering blood pressure by drinking red wine, DrBob Patton also notes that "while resveratrol is usually associated with red wine, this natural compound is present in a variety of fruits and nuts, not just grapes." Excessive drinking leads to higher blood pressure and a range of cardiovascular problems, such as heart attacks and strokesDrinking a glass of red wine may be a way to relax to end a stressful day, but it doesn't help lower blood pressure, and weight loss, regular exercise and stress release are the best ways to control your blood pressuredespite the health benefits of resveratrol and the health benefits of proper red wine, scientific research has not actually confirmed these rumorsIn contrast, studies have shown that drinking alcohol is not good for the bodyRather than relying on the unconfirmed rumors of science, it is better to maintain a healthy lifestyle and a good attitude, is the only way to maintain health and delay agingReference sOleksandra Prysyazhna, et al., (2019)Blood Pressure-Lowering by the Antioxidant Resveratrol is Notinintuitively Mediated by Oxidation of cGMP-Dependent Protein KinaseCirculation, 10.1161/CIRCULATIONAHA.118.037398http://Retrieved May 29, 2019, from http://original title: Red wine blood pressure reduction effect confirmed? Net red resveratrol health effect, experts say?
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