Can the only approved treatment of the premature ejaculation drug hydrochloric acid, Dapositin, save Tyneside?

According to Guangdong Tynekang Pharmaceuticals april 17 issued a notice that the subsidiary Shandong Huapu Kaisheng 4 generic drugs Dapositin n'amphibutinn was approved by the NMPA, the commodity name "Eitting", to this end, Tynekang successfully won the domestic first imitation of Dapositin and as if through the consistency evaluationhydrochloric acid, dapositine, a short-acting selective 5-serotonin reuptake inhibitor (SSRIs), known as "time-lapse Viagra", is suitable for the treatment of 18 to 64-year-old male premature ejaculation (PE) patients, after the domestic only Italian company Menarini's original research drug (commodity name: Bilic) soldthe only approved treatment for PE adaptation sokyepremature ejaculation, the most common ejaculation dysfunction in men, is also causing more and more social concernDapositin is currently the only drug approved for the treatment of PE adaptation certificatesthere is a lot of controversy about premature ejaculationfirst, what is PE? There is currently no uniform definitionAccording to the 2011 Guidelines for The Diagnosis and Treatment of Premature Ejaculation by the Men's Scientific Group of the Chinese Sex Society Sex Society Professional Committee, it is generally defined by two different methods, namely , "objective criteria" and "subjective feelings"The definition of objective criteria is judged by the duration of actual ejaculation and the number of penile jerks; Subjective perception is defined as a situation in which a man ejaculates before the time he or his partner "expects" and who often feels "less control" of ejaculation and/or this condition causes him to be "disturbed", "unsatisfactory" or "difficult to communicate"the prevalence of the disease is also inconsistent, there is no systematic assessment of primary PE and secondary PE prevalenceMost epidemiological studies show that the prevalence of PE is about 20% to 30%the cause ofPE is still unclear, and there is little evidence to support biological and psychological assumptionsIn recent years, scholars' research has been more inclined to PE is caused by several factors, including: high penile head sensitivity, increased excitability of ejaculation center, susceptibility to central 5-serotonin receptors, anxiety, adverse sexual experience, thyroid dysfunction, prostatitis, genetic predisposition, etcbut Dapositin as an approved treatment for PE adaptation certificate sylun is clearDapoxitin is a selective 5-serotonin reabsorption inhibitor (SSRI), the drug principle is by inhibiting 5-serotonin (5-HT) reabsorption, increase synaptic gap 5-HT activity, thereby delaying the ejaculation/sperm impulse, treatment premature ejaculationdapercetin works quickly, the drug has a short half-life, and is quick to remove the body, making it the first-line recommended drug for SSRI on-demand treatment; studies have shown that the ejaculation incubation period (IELT) in the 30mg group and 60mg group is 2.5 times and 3.0 times before treatment, respectively, and both dapositine programmes are effective at the first doseCommon adverse events are nausea, diarrhea, headache and dizzinessDapositin has not yet been approved by the FDA
entering the input of the biliary force in the browser, everywhere the experience of patients to share, similar to "Where can I buy Indian genericdrugs?" According to Insight database, the minimum specification (30mg/tablet) of Bilic won the bid price of about 70 yuan, the original drug in the domestic expensive price has prompted many people to turn to Indian generic drugsin 2013, Menarini announced that through the State Food and Drug Administration approved, the official listing in China, this move to fill the gap in the market for premature ejaculation prescription drugs, from 2013 to date, Willijin exclusive domestic market, domestic will-patent period to 2022Dapositin was first developed by Lilly, incin 2003 and sold to Johnson and Johnson in 2003 to file for approval with the FDA in 2004 for an indication of early ejaculation, but Dapositin has yet to receive FDA approvalBut outside the U.S., the drug is available in 32 countries and territories around the worldItalian drugcompany Menarini has acquired commercial rights to Dapositin, including in Europe, most of Asia, Africa, Latin America and the Middle East, as well as ChinaAccording to Insight database, in addition to Tyneside, there are six companies in the listing of generic drugs, Colum Pharmaceuticals as early as December 2018 to start applying, but the first imitation was taken by TynesideIn addition, there are Chengdu Shengdi Medicine and Taizhou Haichen Pharmaceutical has been approved clinical, registered classified as 3.1 categoryHow big is themen's health drug market?Drugs in men's health have always had huge market spaceThe industry often uses the sales performance of Viagra, Pfizer's first patented drug to treat impotence, to illustrate the market potential in this area, which was approved by the FDA in 1998 and the overall size of the ED market is close to $5 billion, according to public dataa 2013 report that attempted to determine the size of PE patients, the Asia-Pacific Sexual ity and sexual satisfaction survey 2013 found 3,567 people aged 18-45 in nine Asia-Pacific countries and regions, including China, Australia, Korea, Malaysia, the Philippines, Singapore, Thailand, Hong Kong, Taiwan, China, and other countries and regionsThe study concluded that 30 percent of men in China were worried that they were not satisfied with their wife or partner's sex life, 84 percent of them related to premature ejaculation, and that the total number of adult chinese men (18-64 years old) suffering from premature ejaculation had exceeded 460 million, while the attendance rate was extremely low, not more than 7 percent, and the market prospects were promising can Tyneside transform success? Tynekang is a company to start as an agent, marketing expert, long-term agent domestic and foreign drugs and medical equipment, according to its prospectus, drug and medical device sales accounted for more than 70% of the company obtained a number of drugs in China's exclusive agency, such as "and gastrointestinal pills" (gastrointestinal drugs), "lecithin iodine tablets (Wallitin) (eye disease drugs) and so on On 22 August 2019, Tyneside Sprint Science and Technology Board was rejected and policy factors such as "conformity evaluation", "band procurement" and "two-vote system" were included in the sfc's review committee's challenges, or had an impact on revenue sales of generic drugs such as Tyneside would need to be "consistently evaluated", that sales of its prescription drugs and agents' core primary drugs could be squeezed by "band sourcing" and that the "two-vote system" would have a significant impact on Tyneside's drug marketing Tyneside's foreign propaganda has repeatedly stressed the need to strengthen the innovative layout In Tyneside's prospectus, the company has established a strong research and development team as a key step to enhance its core competitiveness The so-called research and development team focuses on "Shandong Huabao Kaisheng" - in October 2015, Tynekang and Changshu Huabao Sincerely jointly funded the establishment of Shandong Huabao Kaisheng, Tynekang holding 55%; , however, the new three-board 2018 annual report shows that its research and development investment is not increasing or decreasing According to the financial report, Tyneand's research and development expenditure in 2018 was RMB23.6565 million, down 13.8% YoY (2017? According to insight database, Tyneside is not working on innovative drugs, and after the listing of Dapositin, it is still working on one generic drug now Tyneside generic drug Dapositin as the first imitation approved, its price is also expensive, in the Tynekang company's announcement that the company has invested in hydrochloric acid Dapositin tablet research and development project spending about 7.597 0 00 million yuan now, the pharmaceutical industry has been in the reshuffle, high-quality generics, innovative drugs are the trend, only those companies that adapt to the development trend of the industry can really stay, to start as an agent, marketing leader Tynekang will also face greater challenges original title: "Time-lapse Viagra" Dapasitin first approved, this only approved treatment of premature ejaculation drug can save Tyneside?