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Cancer Med: Continuous infusion of CD19-CART and BCMA CARTs can effectively and safely treat RRMM

 Last Update: 2021-05-20
 Source: Internet
 Author: User

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In recent studies, the persistent response rate to relapsed and/or refractory multiple myeloma (RRMM) is very low, which indicates that chimeric antigen receptor T cell (CART) therapy has yet to be optimized.

The researchers recruited 10 patients, of which 7 received autologous infusion and 3 received allogeneic infusion.

In summary, these results demonstrate the preliminary tolerability and effectiveness of continuous infusion in RRMM, and propose a simple and safe design suitable for establishing a variety of CART therapies.

Original source:

Lingzhi Yan, et al.

ncbi.
nlm.
nih.
gov/33356013/" target="_blank" rel="noopener">Sequential CD19 and BCMA-specific CAR T -cell treatment elicits sustained remission of relapsed and / or refractory myeloma

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