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Cancer Sci: Aletinib can effectively and safely treat relapsed or refractory ALK-positive lymphoma

 Last Update: 2021-06-10
 Source: Internet
 Author: User

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Inhibition of asexual lymphoma kinase (ALK) is expected to be an effective therapy for ALK-positive malignancies.

Lymphoma

The study included patients with relapsed or refractory ALK-positive ALCL (6 years of age or older).

A total of 10 patients were enrolled, with a median age of 19.

In summary, aletinib shows good clinical activity and is well tolerated in ALK-positive ALCL patients who have progressed with standard chemotherapy.

Original source:

Reiji Fukano, Tetsuya Mori, et al.

Alectinib for relapsed or refractory anaplastic lymphoma kinase -positive anaplastic large cell lymphoma: An open-label phase II trial

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