-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
- Cosmetic Ingredient
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
After the researchers vaccinated volunteers with two injections of inactivated vaccines, they were vaccinated with an adenovirus vector new crown vaccine as a booster.
After 14 days, the neutralizing antibody GMTs was 197.
4 (167.
7, 232.
4), and the antibody level increased by about 78 times; if the third The level of antibody was 33.
6 (28.
3, 39.
8), an increase of about 15.
2 times
.
This data shows that the increase in neutralizing antibody produced after sequential strengthening is significantly better than the effect of homologous strengthening
.
According to the news on the official WeChat public account of Cansino Biology on the 7th, research shows that the use of inactivated vaccines for primary immunization and Cansino Biological Adenovirus Vector New Crown Vaccine Keweisha for enhanced immunization programs shows good safety and immune effects.
It is significantly better than using inactivated vaccines twice
.
A few days ago, Zhu Fengcai’s team, deputy director of the Jiangsu Provincial Center for Disease Control and Prevention, together with Beijing Institute of Biotechnology, Southeast University and other cooperative units, published a special topic entitled "Heterologous prime-boost immunization with CoronaVac and Convidecia" on the preprint platform medRvix for medical and biological papers.
"Academic papers
.
Fengcai Zhu’s team initiated a clinical study of sequential vaccination of the new coronavirus vaccine in May 2021.
This is a randomized, blinded, parallel controlled clinical study that mainly studies the new coronavirus inactivated vaccine (Vero cell) and the recombinant new coronavirus vaccine ( Type 5 adenovirus vector) safety and immunogenicity of sequential vaccination in healthy adults aged 18-59 years in China
.
The results of clinical trials showed that after the CanSino Bio-Adenovirus vector new crown vaccine was strengthened, it showed good safety and no serious adverse reactions related to the vaccine were found
.
After the researchers vaccinated volunteers with two injections of inactivated vaccines, they were vaccinated with an adenovirus vector new crown vaccine as a booster.
After 14 days, the neutralizing antibody GMTs was 197.
4 (167.
7, 232.
4), and the antibody level increased by about 78 times; if the third The level of antibody was 33.
6 (28.
3, 39.
8), an increase of about 15.
2 times
.
This data shows that the increase in neutralizing antibody produced after sequential strengthening is significantly better than the effect of homologous strengthening
.
The level and growth of neutralizing antibody The study also explored basic immunization by means of sequential vaccination
.
Clinical data shows that a dose of adenovirus vector new coronavirus vaccine is vaccinated after one dose of inactivated COVID-19 vaccine.
The neutralizing antibody GMTs is 54.
4 (37.
9, 78), and the antibody level can increase by at least 25.
7 times; if the second dose is vaccinated, In the live vaccine, the neutralizing antibody GMTs is 12.
8 (9.
3, 17.
5), and the antibody level can be increased by 6.
2 times
.
In addition, studies have shown that the use of CanSino's adenovirus vector new crown vaccine for booster immunization can significantly increase the level of neutralizing antibodies, and the level of RBD antibodies has also been significantly increased, and the cellular immune response has been greatly enhanced
.
In summary, the safety and immunogenicity of sequential vaccination with the adenovirus vector neocorona vaccine as the inactivated vaccine is better than the inactivated vaccine for immunization
.
Comparison of RBD-specific ELISA antibody response under different vaccination procedures Previously, the Thai scientific research team published a research report in September 2021, analyzing the chimpanzee adenovirus vector neocorona vaccine for people who have been vaccinated with inactivated neocorona vaccine after sequential vaccination Immune response
.
The research results show that the immune effect of vaccination with one dose of inactivated vaccine followed by another dose of adenovirus vector vaccine is better than that of two doses of inactivated vaccine, and is equivalent to the immune effect of two doses of adenovirus vector vaccine, and pointed out the immunization program It is an effective way to solve the limitation of the types and output of the new crown vaccine [1]
.
In August 2021, the latest research published by the China Institute for Food and Drug Control in the journal Emerging Microbes & Infections shows that the adenovirus vector neocorona vaccine is used for booster immunization after vaccination with an inactivated vaccine, compared with the vaccination program of a single vaccine , The neutralizing antibody level is significantly increased and can produce an efficient cellular immune response.
This data verifies that the adenovirus vector neocorona vaccine for booster immunization can obtain a better immune effect [2]
.
References: [1]https:// Articles in 2020 1 .
Cup! A full paper cup of hot coffee, full of plastic particles.
.
.
2.
Scientists from the United States, Britain and Australia “Natural Medicine” further prove that the new coronavirus is a natural evolution product, or has two origins.
.
.
3.
NEJM: Intermittent fasting is right The impact of health, aging and disease 4.
Heal insomnia within one year! The study found that: to improve sleep, you may only need a heavy blanket.
5.
New Harvard study: Only 12 minutes of vigorous exercise can bring huge metabolic benefits to health.
6.
The first human intervention experiment: in nature.
28 days is enough to improve immunity.
7.
Junk food is "real rubbish"! It takes away telomere length and makes people grow old faster! 8.
Cell puzzle: you can really die if you don't sleep! But the lethal changes do not occur in the brain, but in the intestines.
.
.
9.
The super large-scale study of "Nature Communications": The level of iron in the blood is the key to health and aging! 10.
Unbelievable! Scientists reversed the "permanent" brain damage in animals overnight, and restored the old brain to a young state.
.
.
After 14 days, the neutralizing antibody GMTs was 197.
4 (167.
7, 232.
4), and the antibody level increased by about 78 times; if the third The level of antibody was 33.
6 (28.
3, 39.
8), an increase of about 15.
2 times
.
This data shows that the increase in neutralizing antibody produced after sequential strengthening is significantly better than the effect of homologous strengthening
.
According to the news on the official WeChat public account of Cansino Biology on the 7th, research shows that the use of inactivated vaccines for primary immunization and Cansino Biological Adenovirus Vector New Crown Vaccine Keweisha for enhanced immunization programs shows good safety and immune effects.
It is significantly better than using inactivated vaccines twice
.
A few days ago, Zhu Fengcai’s team, deputy director of the Jiangsu Provincial Center for Disease Control and Prevention, together with Beijing Institute of Biotechnology, Southeast University and other cooperative units, published a special topic entitled "Heterologous prime-boost immunization with CoronaVac and Convidecia" on the preprint platform medRvix for medical and biological papers.
"Academic papers
.
Fengcai Zhu’s team initiated a clinical study of sequential vaccination of the new coronavirus vaccine in May 2021.
This is a randomized, blinded, parallel controlled clinical study that mainly studies the new coronavirus inactivated vaccine (Vero cell) and the recombinant new coronavirus vaccine ( Type 5 adenovirus vector) safety and immunogenicity of sequential vaccination in healthy adults aged 18-59 years in China
.
The results of clinical trials showed that after the CanSino Bio-Adenovirus vector new crown vaccine was strengthened, it showed good safety and no serious adverse reactions related to the vaccine were found
.
After the researchers vaccinated volunteers with two injections of inactivated vaccines, they were vaccinated with an adenovirus vector new crown vaccine as a booster.
After 14 days, the neutralizing antibody GMTs was 197.
4 (167.
7, 232.
4), and the antibody level increased by about 78 times; if the third The level of antibody was 33.
6 (28.
3, 39.
8), an increase of about 15.
2 times
.
This data shows that the increase in neutralizing antibody produced after sequential strengthening is significantly better than the effect of homologous strengthening
.
The level and growth of neutralizing antibody The study also explored basic immunization by means of sequential vaccination
.
Clinical data shows that a dose of adenovirus vector new coronavirus vaccine is vaccinated after one dose of inactivated COVID-19 vaccine.
The neutralizing antibody GMTs is 54.
4 (37.
9, 78), and the antibody level can increase by at least 25.
7 times; if the second dose is vaccinated, In the live vaccine, the neutralizing antibody GMTs is 12.
8 (9.
3, 17.
5), and the antibody level can be increased by 6.
2 times
.
In addition, studies have shown that the use of CanSino's adenovirus vector new crown vaccine for booster immunization can significantly increase the level of neutralizing antibodies, and the level of RBD antibodies has also been significantly increased, and the cellular immune response has been greatly enhanced
.
In summary, the safety and immunogenicity of sequential vaccination with the adenovirus vector neocorona vaccine as the inactivated vaccine is better than the inactivated vaccine for immunization
.
Comparison of RBD-specific ELISA antibody response under different vaccination procedures Previously, the Thai scientific research team published a research report in September 2021, analyzing the chimpanzee adenovirus vector neocorona vaccine for people who have been vaccinated with inactivated neocorona vaccine after sequential vaccination Immune response
.
The research results show that the immune effect of vaccination with one dose of inactivated vaccine followed by another dose of adenovirus vector vaccine is better than that of two doses of inactivated vaccine, and is equivalent to the immune effect of two doses of adenovirus vector vaccine, and pointed out the immunization program It is an effective way to solve the limitation of the types and output of the new crown vaccine [1]
.
In August 2021, the latest research published by the China Institute for Food and Drug Control in the journal Emerging Microbes & Infections shows that the adenovirus vector neocorona vaccine is used for booster immunization after vaccination with an inactivated vaccine, compared with the vaccination program of a single vaccine , The neutralizing antibody level is significantly increased and can produce an efficient cellular immune response.
This data verifies that the adenovirus vector neocorona vaccine for booster immunization can obtain a better immune effect [2]
.
References: [1]https:// Articles in 2020 1 .
Cup! A full paper cup of hot coffee, full of plastic particles.
.
.
2.
Scientists from the United States, Britain and Australia “Natural Medicine” further prove that the new coronavirus is a natural evolution product, or has two origins.
.
.
3.
NEJM: Intermittent fasting is right The impact of health, aging and disease 4.
Heal insomnia within one year! The study found that: to improve sleep, you may only need a heavy blanket.
5.
New Harvard study: Only 12 minutes of vigorous exercise can bring huge metabolic benefits to health.
6.
The first human intervention experiment: in nature.
28 days is enough to improve immunity.
7.
Junk food is "real rubbish"! It takes away telomere length and makes people grow old faster! 8.
Cell puzzle: you can really die if you don't sleep! But the lethal changes do not occur in the brain, but in the intestines.
.
.
9.
The super large-scale study of "Nature Communications": The level of iron in the blood is the key to health and aging! 10.
Unbelievable! Scientists reversed the "permanent" brain damage in animals overnight, and restored the old brain to a young state.
.
.