Carbon penicillin antibacterial drug application specifications issued

Recently, the National Health And Wellness Commission issued "on the issuance of carbon penicillin antimicrobial antimicrobials clinical application expert consensus and other 3 technical documents notice" pointed out that in recent years, China's carbon penicillin antimicrobial drugs in clinical application of some unreasonable phenomena, some bacteria on its resistance to the obvious upward trend, experts recommend strictly grasp the clinical application of clinical evidence of drugs, regulate the application of carbon penicillin antimicrobial drugs in children and special populations. The Regulations on the Evaluation of the Clinical Application of Carbon Penicillin Antibacterial Drugs and the Regulations on the Evaluation of the Clinical Application of Cyclocycline were also issued at the same time.
consensus points out that the National Bacterial Resistance Monitoring Network shows that in 2017, the detection rate of creepy penicillin-resistant pneumoniae was 9.0%, up 2.6 percentage points from 2014, with the highest detection rate in individual provinces reaching 26.9%. In the elderly, children and adults, the detection rate of carbon penicillin-resistant krepus was 10.2%, 9.1% and 7.8%, respectively. The detection rate of carbon penicillin-resistant Bowman bacillus continued to be high, with a national average detection rate of 56.1% in 2017 and a maximum detection rate of 80.4% in individual provinces.
consensus points out that for severely ill patients, the presence of infection needs to be carefully identified before deciding whether antimicrobial drugs, especially carbon penicillin, are needed. Severe patients with multiple drug-resistant bacterial infections are identified by the use of carbon penicillin-type antibacterial drugs. Diversification of antimicrobial treatment for drug-resistant bacterial infections should be promoted. Patients with useful drug adaptation certificates should emphasize pathogen diagnosis, timely step-down treatment, according to the pathogenic bacteria category and antimicrobial pharmacogenics / pharmacological properties to choose the appropriate carbon penicillin varieties. Consensus stressed that multi-drug resistance to plant bacteria or carrying status, should not be used carbon penicillin antibacterial drugs. Hand hygiene and other hospital infection basic prevention and control measures applicable to all drug-resistant bacteria prevention and control. Attention should be paid to active screening of people at high risk of infection with carbon penicillin (CRE), and a screening system for drug-resistant bacteria such as CRE in hospitals should be gradually established to isolate infected and carriers. (Health News)