echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Endocrine System > Cardiovasc Diabetol: Age differences in prediabetes and subclinical atherosclerosis

    Cardiovasc Diabetol: Age differences in prediabetes and subclinical atherosclerosis

    • Last Update: 2022-09-30
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

    Background: The global burden of cardiovascular disease (CVD) has been increasing
    for decades.


    Much of our knowledge about prediabetes as a cardiovascular risk factor comes from studies
    of middle-aged people.


    Because CVD events take a long time to occur, diagnosing subclinical atherosclerosis by an increase in pulse wave velocity (PWV) or an increase in carotid linar thickness (CIMT) can better assess the impact
    of prediabetes on the development of pronounced CVD in a relatively short period of time.


    In addition, the association between different prediabetes subtypes and CVD may be different
    .


    Objective: Here, we compared the relationship between prediabetes and blood glucose indicators and subclinical atherosclerosis between middle-aged people (40-59 years old) and older people (≥ 60 years old) using the prediabetes threshold recommended by the American Diabetes Association (ADA) 2021 standard, and the causal relationship
    between blood glucose indicators and PWV in the prospective cohort of China in the cross-lag panel model.


    Methods: We included 4739 individuals aged ≥ 40 years with no history of diabetes or CVD and divided them into middle-aged (age < 60 years) and elderly (age ≥ 60 years).


    Results: Of the 1634 participants over the age of 60, 64.


    Table 1 Relationship between prediabetes, IFG, IGT and elevated HbA1c and increased baPWV in the elderly population

    Figure 1 Age-related correlation
    between glycemic measurements and OR (95% confidence interval) of elevated baPWV.


    Table 2 Adjusted cross-lag standard regression coefficients for baPWV and FPGs

    Table 3 Adjusted cross-lag standard regression coefficients baPWV and 2 h-PPG

    Table 4 Adjusted cross-lag standard regression coefficients for BaPWV and HbA1c

    Conclusions: Our findings suggest that older patients with prediabetes may have a smaller relationship with subclinical atherosclerosis than middle-aged people, and suggest that age is an important consideration
    when treating patients with pre-age diabetes.


    Original source:

     

    Cao Q, Xin Z, He R,et al.


    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.