Cardiovasc Diabetol: Cardiac magnetic resonance tissue tracking to evaluate the cumulative effect of aortic regurgitation on left ventricular strain in patients with type 2 diabetes mellitus

Background: Type 2 diabetes mellitus (T2 DM) and its associated cardiovascular disease pose a growing burden in terms of morbidity and mortality
.

T2DM is characterized by insufficient or ineffective insulin utilization, resulting in chronic hyperglycemia

2 DM is characterized by insufficient or ineffective insulin utilization, resulting in chronic hyperglycemia

Cardiac magnetic resonance (CMR) tissue tracking techniques, based on post-processing of standard steady-state free-precessing cine images, have emerged as a widely accepted imaging tool for quantifying diabetes-related cardiac dysmorphic dysfunction

Table 1 Comparison of CMR results between patients with type 2 diabetes mellitus with/without AR and normal controls

Table 1 Comparison of CMR results between patients with type 2 diabetes mellitus with/without AR and normal controls

Table 2 Comparison of left ventricular strain in patients with mild, moderate and severe type 2 diabetes mellitus and normal controls

Table 2 Comparison of left ventricular strain in patients with mild, moderate and severe type 2 diabetes mellitus and normal controls

Figure 1.
CMR-derived LV strain parameters for control, T2 DM (AR-) and T2 DM (AR+) in LV PS (%), PSSR (1/s), PDSR (1/s)
.

#T2 DM patients with AR and T2 DM patients without AR#P<0.

Figure 1.

Figure 2.
Cardiac cine images and three-dimensional pseudocolor images of left ventricular longitudinal strain in patients with T2 DM with mild, moderate, and severe regurgitation
.

Ac-T2 DM with severe aortic insufficiency, male, 59 years old, left ventricular short-axis (A), four-chamber (B), double-chamber (C), Rf=68.

Figure 2.

AR can exacerbate LV stiffness in patients with T2 DM, resulting in decreased LV strain and function

Additive effect of aortic regurgitation degree on left ventricular strain in patients with type 2 diabetes mellitus evaluated via cardiac magnetic resonance tissue tracking.
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